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Protein Synthesis
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Write down 5 “things” that you know about DNA
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What is a GENE? Instruction manual for our body
They are the directions for building all the proteins that make our body function
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Where is a Gene? Within DNA
The nitrogen bases spell out the instructions.
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What is a TRAIT? A trait is a genetically determined characteristic
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RNA Ribonucleic Acid Make up of Nucleotides Contains Phosphorus
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RNA Nucleotide A C B Uracil Phosphate Nitrogen Base Guanine Cytosine
Ribose Adenine Uracil
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Types of RNA Messenger RNA Nickname: mRNA
Made up of ONE strand of nucleotides
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mRNA Function Copy a message from a gene on DNA DNA mRNA
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Types of RNA Transfer RNA Nickname: tRNA
Made up of ONE strand of nucleotides and a amino acid
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Carries amino acids to mRNA
tRNA Function Carries amino acids to mRNA Amino Acids mRNA
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Types of RNA Ribosomal RNA Nickname: rRNA
Made up of ONE strand of nucleotides mixed with the ribosome
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Forms peptide bonds between the amino acids
rRNA Function Forms peptide bonds between the amino acids rRNA Peptide Bond Amino acid Amino acid Amino acid Amino acid
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DNA versus RNA: # of Strands
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DNA versus RNA: Sugar Deoxyribose Ribose
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DNA versus RNA: Bonds with Adenine
Thymine Adenine Uracil
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Review: Protein Synthesis
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Brief summary of Protein synthesis
Make Proteins
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Brief Summary of Transcription
Make mRNA from a gene on DNA
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Location of Transcription
Nucleus
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Process of Transcription
DNA Backbone Nitrogen Bases T A C G C G C C T A G G A T T A G T A T G C G C G G A T C C T A A T C A RNA Polymerase RNA Polymerase attaches to DNA and breaks Hydrogen bonds; splitting DNA Choose a gene that needs to be “read” or copied
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Process of Transcription
DNA RNA Polymerase T A C G C G C C T A G G A T T A G T A T G C G C G G A T C C T A A T C A A U G C G C G G A U C C U A A T C A mRNA RNA polymerase adds matching nucleotides to exposed DNA strand DNA is split apart; separated Nitrogen Bases DNA Backbone A T G C G C G G A T C C T A A T C A
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Process of Transcription
DNA RNA Polymerase T A C G C G C C T A G G A T T A G T A T G C G C G G A T C C T A A T C A A U G C G C G G A U C C U A A U C A mRNA mRNA leaves the nucleus RNA Polymerase leaves DNA recombines A U G C G C G G A T C C T A A T C A mRNA Nitrogen Bases DNA Backbone A T G C G C G G A T C C T A A T C A
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Transcription Animation #1 Transcription Animation #2 Transcription Video
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Transcribe the following
DNA TAC GGC AAA TAG GAT TTT CCA TTA AGT AUG CCG UUU AUC CUA AAA GGU AAU UCA mRNA
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