1. Blood Type December 1, 2009

2. Catalyst Answer and turn in!!! (not open book!) What are the four parts of blood?

3. Contents of Blood Plasma (55%) Erythrocyes Leukocytes Platelets

4. Aim What differentiates one blood type from another? Learning Target! I CAN explain what differentiates one blood type from another

5. A-G-E-N-D-A- Catalyst Brainstorm Lesson Practice

6. BRAINSTORM! List as many blood types as you know!

7. Our list...

8. 4 main types A B AB O

9. Brief History 1901 Karl Landsteiner Later won the Nobel Prize Developed the A-B-O System

10. Impact Led to successful blood transfusions Millions of lives have been saved

11. So, what makes A different from B different from O? Presence of an antigen on the surface of an erythrocyte Antigen- a substance, usually a protein, that stimulates the body to produce antibodies against it

12. If you are type A You have an A antigen on your erythrocytes

13. If you are type B You have a B antigen on your erythrocyes

14. If you’re type AB, you have both

15. If you’re type O, you have neither

16. Blood plasma has proteins called ANTIBODIES What do you know about antibodies?

17. Antibody A protein in the blood serum that destroys or inactivates a specific antigen Have a specific shape A antibodies react with A antigens B antibodies react with B antigens

18. Type A people have B antibodies

19. Type B people have A antibodies

20. Tybe AB people DON’T have antibodies

21. Type O people have BOTH antibodies

22. Pulse.check. If you have type A blood, what is your antigen, what are your antibodies? Antigen = A Antibody = B

23. Pulse check. If you have type O blood, what are your antigens and antibodies? Antigens – none Antibodies – A and B

24. ABO - prevalence in US Blood Type% A42 B10 AB4 O44

25. When an antibody reacts with an antigen, agglutination occurs Agglutination – the clumping together of red blood cells by the action of an antibody