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Biological Molecules John Ireland Chapter 3 Bio162
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Carbon, The Organics CarbohydratesNucleic Acids ProteinsLipids
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Carbon, the Organic Element
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Biological Molecules are Organic
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Functional Groups, subunits of structure
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Hydroxyl (- OH)
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Carboxyl (- COOH)
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Amino (-NH 2 )
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Sulfhydryl (-SH)
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Phosphate (PO 4 )
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Methyl (-CH 3 )
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Together these groups give organic molecules their functions
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How do we go from small molecules to large polymers?
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Dehydration Reaction
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H HO H
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How do we break them back apart?
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Hydrolysis
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HO H H
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Carbohydrates, the Sugars
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Carbohydrates are polymers of Simple Sugars
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Carbohydrates have two functions
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Function comes from Structure
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Structure comes from the arrangement of monomers
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New Arrangement = New Function
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Nucleic Acids, Information
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Nucleic Acids are polymers of nucleotides
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Nucleic Acids have two functions
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Heredity
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Energy Transfer
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Function is determined by the order of nucleotides
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Proteins, Diverse Functions
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Proteins are linear polymers of amino acids
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Amino Acids have an amino and a carboxylic acid functional group
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There are twenty natural amino acids.
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In essence, they are a chemistry tool kit.
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Amino Acids bind together by peptide bonds
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Proteins are extremely varied in Function
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Function is derived from Structure
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Structure is an emergent property.
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There are four levels of structure.
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Now pull them together…
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Evolution likes to reuse what works.
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A protein’s function is destroyed if the structure is destroyed (denatured).
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Lipids, Diverse Structures
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Lipids are polymers composed of the monomer acetyl-CoA
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Very diverse structures can be formed.
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Trigylceride
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Phospholipid
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Sterols/Steroids
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Lipids have three functions
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