1. Copyright © 2010 Pearson Education Inc. Lecture 02 – Mendelian Genetics Based on Chapter 11 – Mendelian Genetics

2. 1. Introduction

3. 2. Genotype and Phenotype

4. 3a. Mendel’s Experimental Design Mendel used garden peas ( Pisum sativum ) Established “true breeding” plants –Now called inbred plants Carefully made crosses between true breeding lines Mathematically analyzed the results of the crosses and subsequent generations of plants.

5. 3b. Mendel’s Experimental Design

6. 4a. Monohybrid Crosses and Mendel’s Principle of Segregation Terminology used in breeding experiments: Parental generation is the P generation. Progeny of P generation is the first filial generation, designated F1. When F1 interbreed, the second filial generation, F2, is produced. Subsequent interbreeding produces F3, F4, and F5 generations.

7. 4b. Monohybrid Crosses and Mendel’s Principle of Segregation

8. 4c. Monohybrid Crosses and Mendel’s Principle of Segregation

9. 4d. Monohybrid Crosses and Mendel’s Principle of Segregation

10. 5a. The Principle of Segregation

11. 5b. The Principle of Segregation

12. 6a. Dihybrid Crosses and Mendel’s Principle of Independent Assortment

13. 6b. Dihybrid Crosses and Mendel’s Principle of Independent Assortment 1.

14. 6c. Dihybrid Crosses and Mendel’s Principle of Independent Assortment

15. 6d. Dihybrid Crosses and Mendel’s Principle of Independent Assortment

16. 6e. Dihybrid Crosses and Mendel’s Principle of Independent Assortment The “Rediscovery” of Mendel’s Principles Mendel’s work was published in 1866 –received little attention from the scientific community until about 1900 –Correns, deVries, and von Tschermark independently conducted experiments with similar results. In 1902 William Bateson, experimenting with fowl, showed that Mendelian principles apply in animals. –He coined the terms genetics, zygote, F1, F2, and allelomorph (which was shortened to allele). W. L. Johannsen named Mendelian factors genes in 1909, from the Greek genos, meaning “birth.”

17. 7a. Mendelian Genetics in Humans

18. 7b. Mendelian Genetics in Humans

19. 7c. Mendelian Genetics in Humans

20. 7d. Mendelian Genetics in Humans