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Protein Synthesis. Translation Overview One codon One amino acid.

Published byLeslie Short Modified over 9 years ago

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Presentation on theme: "Protein Synthesis. Translation Overview One codon One amino acid."— Presentation transcript:

1 Protein Synthesis

2 Translation Overview One codon One amino acid

3 Transfer RNA

4 Ribosome Codon-anticodon matching Peptide bond formation

5 Transcription/TranslationATGCCGTTTGAGGCCTGA TACGGCAAACTCCGGACT UAGCCGUUUGAGGCCUGA

6 PAE AAA AUGCCGUUUUAGGCCUGA GGC AminoacylSite Exit Site UAC Peptidyl Site MetPhePro

7 PAE AAA AUGCCGUUUUAGGCCUGA GGC MetProPhePro

8 Wobble Only 45 different tRNA molecules exist Pairing of the anticodon with the third base of the codon is less specific

9 Protein Processing Ribosome type depends on ultimate destination of polypeptide FreeBound Polypeptide to be used in cytosol Polypeptide is headed to membrane or beyond via ER

10 Protein Processing Signal Peptide Signal Recognition Particle Receptor Protein Polypeptide fed into cisterna Rough ER Cytosol

11 DNA Function Review 1.What are the three sites in a ribosome? 2.Spliceosome:Intron::_____:_____ 3.How is location of translation related to the eventual use of its product? 4.What is wobble?

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