1. Translation  Catalyst:  DNA is the genetic code. What part of DNA is the genetic code? Choose an answer and then explain why the other choices are wrong. A.The phosphate-sugar backbone B.The sugar C.The phosphate D.The base sequence  Convert this strand of DNA into mRNA. AGCATCGAGTAA

2. Agenda  Catalyst Review  HW Review  Transcription/Central Dogma Review  Translation  Codon Bingo  ROBBERY MYSTERY!  Exit Question

3. Catalyst Review  DNA is the genetic code. What part of DNA is the genetic code? Choose an answer and then explain why the other choices are wrong. A.The phosphate-sugar backbone B.The sugar C.The phosphate D.The bases  The bases must be the code since they form a sequence that changes throughout DNA.  Sugar-phosphate backbone holds the DNA’s shape.

4. Catalyst Review  Complimentary base pairing!  Except…  AGCATCGAGTAA  UCGUAGCUCAUU RNA loves U

5. HW Review

6. Objectives  By the end of today, SWBAT…  Translate DNA and mRNA into an amino acid sequence.  Describe the relationships among DNA, RNA, proteins, and traits.

7. USE THE DNA CODE PROVIDED TO MAKE A COMPLEMENTARY RNA COPY U C G A G C C T G T A G G C A G A CA U CC G U

8. USE THE DNA CODE PROVIDED TO MAKE A COMPLEMENTARY RNA COPY C G U G C A T T C A A G C A T A A GU U CG U A

9. Describe two reasons why this is TRANSCRIPTION…

10. Time for Notes…. Get ‘em out!

11. Translation  Key Point #1:  Translation is the process by which the ribosome reads the mRNA and uses its information to make protein Protein mRNA

12. The mRNA code  The ribosome reads the mRNA one codon at a time.  A codon is a set of three bases.  Every codon contains the information to make one amino acid.  Many amino acids make up a protein.

13. Table of CODONS Third Letter From your three letter codon, you can use this table to figure out what amino acid it is.

14. Let’s Practice  Codon: UAC  What is the amino acid? Tyrosine!

15. Codon BINGO!!!

16. What are proteins used for again?  Proteins go on to cause ALL traits. They are important.  Key Point #3:  If you change someone’s DNA, that will change its traits.

17. Add to the Central Dogma???? DNA RNA Protein (Trait) a change here… means a change here and here and finally here

18. Guided Practice (GP)  Read over key points and your notes.  I am going to ask questions, with a 25 second timer. You should be able to find the answer. If not—add it in!  Raise your hand when you find the answer.

19. Look in your NOTES! What is translation?

20.  Why is this picture showing TRANSLATION?

21. NOTES NOTES NOTES What is a codon?

22. How many bases make up a codon?

23. What do all mRNA sequences end in?

24. What happens when you change the DNA bases in a gene?

25. One protein causes brown eye color, another causes blue. What is different about the DNA that produces these two proteins?

26. OH MAN THERE WAS A ROBBERY  But luckily they have some DNA evidence.  Weirdly, they asked me to get my Biology class to solve it!  Make sure you make a sketch of the suspect! That jerk!

27. Exit Question  Convert this strand of DNA to an amino acid sequence.  AAACAAGCACCC  If you change someone’s DNA, their traits will change. Explain why this is true.