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Metabolism
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Defining Energy Potential energy is the capacity to do work. Kinetic energy is the energy of motion. ATP is the cell’s energy source
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Potential energy of molecules is known as chemical energy. Energy that is not given off as kinetic energy is given off as thermal (heat) energy. Heat energy is considered “wasted energy”
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Laws of Thermodynamics First law –Energy is not created or destroyed only transferred between forms. The total amount of energy in the universe remains constant.
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Second law -- No energy conversion can ever be 100% efficient. Energy always flows from more useful forms of energy to forms that are less useful.
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Endergonic reaction Uphill reaction Energy is put into the reaction For example: Glycolysis
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Exergonic reaction Downhill reaction Energy is released during the reaction Example: The Kreb’s cycle and electron transport system
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ATP Adenosine Triphosphate Consists of a 5 carbon sugar and 3 phosphate groups. It is the cell’s energy source To release energy, it will break a bond between phosphates
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Enzyme Structure & Function Enzymes – speed up the rate of a reaction. Also called a catalyst Equilibrium - when a reaction is running at the same rate forward as well as in reverse.
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Four shared features 1. Enzymes do not make anything happen that could not happen on its own, it just makes it happen faster. 2. Reactions do not permanently change or use up an enzyme
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3. The same type of enzyme usually works whether the reaction is occurring in a forward or reverse motion 4. Each type of enzyme is very picky
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Enzyme-Substrate interactions Activation energy - the energy that must be provided in order for the reaction to begin. Enzymes lower the amount of activation needed to begin a reaction.
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Enzymes have one or more active sites At these places, enzymes interact with their substrate.
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Active Site A specific shape that will only fit a specific substrate. (Like a lock & Key). When the substrate locks into the active site, the reaction can begin with a lower activation energy because bonds are weakened within the molecule.
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Factors influencing Enzyme Activity 1. Temperature – enzymes only work in a certain temperature range 2. pH – measure of amount of acid or base in the solution
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3. Salinity – measure of salt content in the solution 4. Feedback Inhibition – mechanism where a cellular change that resulted from an activity stops the activity that caused the change
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Working with and against a concentration gradient A concentration gradient is the difference in the number of molecules of a given substance in two adjoining regions.
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In the absence of an opposing force, molecules move from an area of high concentration to an area of low concentration
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Diffusion The net movement of like molecules from high concentration to low concentration (also called down the gradient)
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Passive Transport Requires no extra energy in order to occur. The flow of dissolved material across a membrane through transport proteins following the concentration gradient. If allowed to, this movement would occur until both areas had equal concentration of the solutes.
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Osmosis The diffusion of water molecules across a semi-permeable membrane.
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Hypotonic solution When too much water is moving into the cell and not enough water is leaving the cell
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Hypertonic solution When too much water is leaving the cell and not enough is entering. Water tends to diffuse from hypotonic solution to hypertonic solutions
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Isotonic solutions Water is moving equally into and out of the cell. Cell is in a state of equilibrium
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Active Transport Movement across the membrane against the concentration gradient. This movement requires energy. ATP provides the energy.
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Vesicle Formation Molecules too large to be transported by carrier proteins are moved into or out of the cell by vesicle formation.
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Exocytosis A vesicle fuses with the membrane and secretion occurs.
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Endocytosis Cells take in substances by vesicle formation.
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Phagocytosis When the material taken in is large and usually a “food”
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Pinocytosis Occurs when the particles taken in are a liquid.
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Works Cited http://biology.unm.edu/ccouncil/Biology_124/Im ages/tonicity1.jpeg http://biology.unm.edu/ccouncil/Biology_124/Im ages/tonicity1.jpeg http://www.greenscreen.org/articles_sr/energy/i mages_potential_kinetic_energy/potential_kinet ic.jpg http://www.greenscreen.org/articles_sr/energy/i mages_potential_kinetic_energy/potential_kinet ic.jpg http://regentsprep.org/Regents/biology/units/ho meostasis/lockkey.gif http://regentsprep.org/Regents/biology/units/ho meostasis/lockkey.gif http://bassethound.files.wordpress.com/2007/04 /sharris-deptofentropy.gif http://bassethound.files.wordpress.com/2007/04 /sharris-deptofentropy.gif
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