1. TAYLOR ARLEDGE, NNEOMA OBIESHI, ANGELINA BAJRA Hemophilia

2. What is Hemophilia? Hemophilia is an X linked recessive blood disease  Most common in Caucasian men, as most x liked genetic disorders  Results from a deficiency in the clotting factor  Often called Christmas Disease or the Disease of the Royals Hemophilia A and Hemophilia B  Hemophilia A would be the most common out of the two  due to the decreased activity of factor VIII which aids in clotting  Hemophilia B is much like Hemophilia A except the deficiency involves Factor IX  Known as Christmas Disease

3. How is Hemophilia inherited? How the disorder is inherited?  Through a carrier Mother or a Hemophiliac Father (paired with normal mates or combined Can someone be a carrier for Hemophilia  Women are always the carriers of this disease  Women have two x chromosomes and can only he hemophiliacs if they hare homozygous for the recessive trait

4. Inheritance patterns

5. Symptoms include How the disease is diagnosed  Excessive bleeding  Bleeding in the joints  Joint scarring  Bruises  Hemorrhage Demographics  “Hemophilia A affects between one in 5,000 to one in 10,000 males in most populations.”(Gale )  Genetic testing  Amniocentesis DNA testing of fetal cells shed into the amniotic fluid for genetic mutations.  chorionic villus sampling examines proteins for the defects that lead to hemophilia. (gale) Symptoms & Diagnosis

6. Treatment and Cures Treatment  Usually the patient is injected with the deficient factor  Hemophiliacs A receiving Factor VIII  Hemophiliacs B receiving Factory IX  Other simpler modes of handling this disorder are wearing protective clothing on bodily areas that go through much contact as in the hands feet or arms. Effectiveness of Treatmnent  the treatment is used in emergency settings only and not daily administered.  Works when needed.

7. Works Cited Wilson, Jennifer F. "Hemophilia." Gale Virtual Reference Library. Ed. Brigham Narins. Vol.1 and 2 ed. N.p., 2006. Web. 7 Feb. 2011. <http://go.galegroup.com/ps/ i.do?&id=GALE%7CCX3451500193&v=2.1&u=s0351&it=r&p=GVRL&sw=w "What Is Hemophilia, Hemophilia A, and Hemophilia B?" National Heart, Lung and Blood Institute. July 2009. Web. 07 Feb. 2011.. Raabe, Michelle, Ph.D. Hemophilia. New York City: Chelsea House, 2008. Print Pacheco, Maria. "Hemophilia." Magill's Medical Guide. Ed. Dann P. Dawson. Vol. 3. Pasadena, California: Salem Press Inc., 2008. 1282-1285. Print. “Hemophilia." Human Diseases and Conditions. Ed. Niel Tzenburg, M.D. New york, New York: Charles Scribner's and Sons, 2000. 434-438. Print.