1. Bone Control Design™ Implant surface osseoconductivity Factor 1

2. Bone Control Design™- 2 3. Implant surface osseoconductivity 1  Relation to crestal bone maintenance  Improved osseointegration may lead to improved bone maintenance  Implementation in Straumann® Bone Level implants  By using SLActive™ all surface benefits apply  Accelerated osseointegration*  Increased treatment predictability*  Reduced healing times  Increased confidence  Supporting evidence  SLActive™ studies (15 published)  Studies with SLA® (over one hundred published) * When compared to SLA

3. Bone Control Design™- 3 Histology 12 weeks Becker J, Schwarz F (Heinrich-Heine University, Düsseldorf, Germany) Data presented at 15th Ann. Sci. Meeting of the EAO, Zurich, 2006 SLA ® New bone SLActive™ Artificial bone defect 3. Osseoconductivity 1

4. Bone Control Design™ Microgap control Factor 2

5. Bone Control Design™- 5 1.Microgap control 2 Supporting evidence  Microgap measurements  Mechanical stability of system to lateral forces Relation to crestal bone maintenance  microgap  bacterial contamination  inflammation (peri-implantitis)  bone resorption Implementation in Straumann ® Bone Level implants  Conical Connection  The conical connection is designed to provide a seal and minimize the sensitivity to lateral forces

6. Bone Control Design™ Biomechanical implant design Factor 3

7. Bone Control Design™- 7 4. Biomechanical implant design Relation to crestal bone maintenance  Strength to withstand chewing forces  Bone must be stimulated in a certain range to be maintained and not overused or resorbed Implementation in Straumann ® Bone Level Implant  Excellent fatigue strength  Flat neck portion, similar to S/SP/TE implants  Excellent force transmission with a novel connection design  Tapered Effect thread geometry Supporting evidence  Fatigue testing, finite element (computer simulated) testing  Preclinical and clinical data 3

8. Bone Control Design™ Respecting the biological distance Factor 4

9. Bone Control Design™- 9 5. Respecting the biological distance 4 Relation to crestal bone maintenance  Respecting the biological distance is a key factor for preserving the crestal bone level Implementation in Straumann ® Bone Level Implant  BL: horizontal offset (biological distance)  TE: vertical offset (biological distance)  Keep the microgap away from the bone Supporting evidence Preclinical animal studies with the Straumann® Bone Level Implant Microgap origin of bacterial contamination 0.4 mm *

10. Bone Control Design™ Position of smooth and rough surface Factor 5

11. Bone Control Design™- 11 2. Optimal position of smooth and rough surface Relation to crestal bone maintenance  A rough surface that extends over the bone crest has the tendency to preserve crestal bone Implementation in Straumann ® Bone Level Implant  The rough/smooth surface interface of the Straumann ® Bone Level Implant is located at the top of the implant shoulder  Surgical Procedure: The Straumann ® Bone Level Implant is generally placed at bone level Supporting evidence  Preclinical animal studies with the Straumann ® Bone Level Implant 5