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During the study period 53 retrievals for MVIT were completed, all of which were performed by a Consultant Transplant surgeon. The median distance from.

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Presentation on theme: "During the study period 53 retrievals for MVIT were completed, all of which were performed by a Consultant Transplant surgeon. The median distance from."— Presentation transcript:

1 During the study period 53 retrievals for MVIT were completed, all of which were performed by a Consultant Transplant surgeon. The median distance from base hospital to donor hospital was 141 miles (range 0-452 miles) and the median travel time was 2hrs 20mins (range 0-6hrs 10mins). Overall, the travel zone for retrievals covered approximately 175,000 square miles. Travel was by aeroplane in 16 cases (30%). The median time from knife-to-skin to cold perfusion was 4hrs 25mins (range 2hrs 30mins – 9hrs 20mins) and the median overall operative time was 5hrs 57mins (range 4hrs 4mins – 10hrs 28mins). This was in part dictated by progress in the recipient explant procedure, which often necessitated delay in cross clamp to minimise unnecessary cold ischaemia. The mean cold ischaemic time was 4hrs 42mins (range 2hrs 27mins – 6hrs 50mins). There was no organ damage requiring surgical repair in any of the retrievals. NATIONWIDE ORGAN RETRIEVAL FOR ADULT MULTIVISCERAL AND INTESTINAL TRANSPLANTATION IN THE UK AD Barlow, I Amin, L Sharkey, C Rutter, NKI Russell, SJ Middleton, NV Jamieson, AJ Butler adambarlow@doctors.net.uk Multi-visceral and intestinal transplantation (MVIT) is increasingly viewed as the treatment of choice for irreversible intestinal failure and complications of parenteral nutrition Given the low numbers and technical complexities of the procedure, retrievals are not part of the UK national organ retrieval service and each of the four centres procures their own organs for MVIT. This can provide challenges in minimising cold ischaemia, the limit of which is generally accepted as 6 hours for small bowel. This study reports the experience of one centre in providing a nationwide adult MVIT retrieval service. INTRODUCTION 226 CONCLUSIONS METHODS RESULTS All retrievals for MVIT over a six-year period between January 2009 and January 2015 were included. Data were collected from the unit’s prospectively maintained transplant database. All organs were retrieved from donation after brain donors. Warm dissection involved full mobilisation of the entire intestine from gastro-oesophageal junction to sigmoid colon, liver, spleen and pancreas. The SMA and coeliac axis were fully isolated and slung. Cold perfusion was performed via an aortic cannula with at least 10 litres of University of Wisconsin solution. Organ blocks were retrieved with a large aortic patch comprising the coeliac axis and superior mesenteric artery. This study demonstrates that it is logistically feasible to provide a MVIT organ retrieval service in the UK with nationwide cover, with very acceptable cold ischaemic times. However, the resources required are significant in terms of personnel, travel costs and theatre usage in the donor hospital. RESULTS Figure 1. Location of donor hospitals for multi-visceral/intestinal retrievals Sex (M:F) (%)34:66 Age (median (range))33 (9-63) BMI (median (range))22.1 (15.2-27.9) Cause of death (%) Intracranial haemorrhage Hypoxic brain injury Intracranial trauma Other 47 19 17 Table 1. Donor demographics


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