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Published byRosamund Moody Modified over 9 years ago
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Or Ion Channels, Action Potentials, and other “shocking” things about the brain (the most “current” information available!)
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Basic Unit of Neuropsychology Golgi Stain shows anatomy of neurons Nissl Stain shows number of neurons in a given area
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Because of excess K+ ions inside the cell membrane the neuron is polarized When enough excitatory neurotransmitters bind, the neuron depolarizes and ‘fires’
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Place an electrode on a single neuron and measure the frequency of firing. Can also do single cell stimulation – pleasure center studies
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Strokes Aspiration Lesions Cryogenic Blockade External Injuries – Picture is Phineas Gage’s actual skull!
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Spatial Resolution – How close in physical proximity you can get to the target brain area Temporal Resolution – How close in time you can get to when the neurons fire Invasiveness – The extent to which foreign substances are introduced to the body. Cost – All are really expensive
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Measures O 2 flow to different brain areas
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Good Spatial Resolution, poor temporal resolution, completely non-invasive
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Measures 2-deoxyglycose flow to brain areas
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Excellent Spatial Resolution, poor temporal resolution, somewhat invasive
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Measures magnetic signals associated with neural firing in brain areas
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Poor spatial resolution, excellent temporal resolution, completely non-invasive
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Measures light absorption associated with neural firing in brain areas
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Good, but limited spatial resolution, excellent temporal resolution, completely non-invasive
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Sends current through the scalp to activate different neural regions
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Good Spatial Resolution, Excellent temporal resolution, highly invasive
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Good Neuropsych studies look for dissociations: Brain Area 1 Brain Area 2 Task 1Task 2 Activation No Activation
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Hippocampal lesions and the case of H.M.
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Anterograde vs. Retrograde Amnesia Short Term vs. Long Term Memory Implicit vs. Explicit Memory Bilateral Removal of the Hippocampus
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Famous dissociation is the Fusiform Gyrus
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