1. Beginning of the chapter Thrombosis and genetics (Thrombo Sensor) 36

2. SENSORS THROMBO SENSOR Thrombosis

3. SENSORS THROMBO SENSOR Skin surface Blood vessels Blood platelets

4. SENSORS THROMBO SENSORFV Prothrombin FACTOR V (inactive) PROTHROMBIN (inactive)

5. SENSORS THROMBO SENSOR FACTOR V PROTHROMBIN

6. SENSORS THROMBO SENSOR

7. SENSORS THROMBO SENSOR

8. SENSORS THROMBO SENSOR Factor V activated Thrombin (active)

9. SENSORS THROMBO SENSOR

10. SENSORS THROMBO SENSOR

11. SENSORS THROMBO SENSOR APC

12. SENSORS THROMBO SENSOR

13. SENSORS THROMBO SENSORFV Prothrombin FACTOR V PROTHROMBIN

14. SENSORS THROMBO SENSOR FACTOR V (mutation) PROTHROMBIN

15. SENSORS THROMBO SENSOR FACTOR V (mutation)

16. SENSORS THROMBO SENSOR

17. SENSORS THROMBO SENSOR APC

18. SENSORS THROMBO SENSOR

19. SENSORS THROMBO SENSOR Stroke Pulmonary embolism Thrombosis Heart attack

20. SENSORS THROMBO SENSORFV Prothrombin Venous thrombosis risk PAI1 Arterial thrombosis risk 5 to 25 times increased risk 8 to 80 times increased risk 1.84 times risk

21. SENSORS Risk factors for thrombosis 10 h sitting (plane) Smoking Surgery/bed rest Women: Hormonal preparations contraceptive pill Hormone replacement therapy Women : pregnancy ? 1.52-times risk ? 2-times risk 4-times risk

22. End of the chapter Thrombosis and genetics (Thrombo Sensor) 36