1. HAPPY FRIDAY Bellwork:
1. Have out your Notecard Sticker Sheet. Lay out your notecards (definition side up) on your desk 3x4 (3 rows, 4 columns) “Uracil” needs to be top left card.
2. Copy the paragraph and fill in the missing blanks.
Copy the paragraph on a sheet of paper and fill in the blanks using these words:
Transcription, Uracil, Nucleus, DNA, RNA, U, Ribose, exact, DNA, Replication, RNA, Transcription, protein, Central Dogma, RNA
________ is the process in which ____ is used to make ______. This process occurs in the ________ of the cell. RNA contains the nitrogen base ________, also referred to as ___. RNA contains the sugar _______.
The ________ _______ states that _____ makes ______, which then makes _______. ____________ is the process that uses DNA to make an ________ copy of DNA. ______________ is the process in which DNA is used to make _______.
Transcription
DNA
RNA
Uracil
Nucleus U
Ribose
Central Dogma
DNA
RNA
Protein
Replication
exact
Transcription
RNA

2. Collect Today Notecard Definitions (Due Today) Page 50 - Code Breaker (Due Today) DNA Structure Quiz (Thursday) Assigned Notecard ALL PARTS (Due Wednesday) Late Page 45 – DNA Candy Replication (-50%) Page 46 – Comic Book Strip (-30%)

3. Definitions list found on my website
Unit 3.2 – Protein Synthesis Definitions Due Today (10/26/15) All Parts Due Wednesday (10/28/15)
Uracil
Gene
Transcription
Ribonucleic Acid (RNA)
Translation
Transfer RNA (tRNA)
Central Dogma
Messenger RNA (mRNA)
Ribosome
Gene Expression
Codon
Anticodon
Definitions list found on my website

4. How is the information on messenger RNA translated into a protein?
Essential Question
How is the information on messenger RNA translated into a protein?
Standard
B.6C – Explain the purpose and process of transcription and translation using models of DNA and RNA

5. Remember our analogy from yesterday…
Remember our analogy from yesterday…. DNA = master copy of building plans RNA= blueprint for one room of building Protein= actual bricks that make up the building Nucleus = boss’ office Ribosome = assembly line (where the bricks are laid and a wall is built)

6. Proteins are assembled on a ribosome
The decoding of an mRNA message into a polypeptide chain is known as translation.
Proteins are assembled on a ribosome
OUTSIDE of the nucleus (in the cytoplasm)

7. Steps of Translation (Overview)
mRNA travels to the ribosome
Transfer RNA (tRNA) brings the right amino acid to the ribosome
A polypeptide (protein) is formed

8. How does tRNA “know” what amino acid to bring?

9. The genetic code (mRNA) is read three bases at a time
The genetic code (mRNA) is read three bases at a time. Each three-letter “word” is known as a codon. tRNA “looks” for the codon that pairs with its 3 nucleotide sequence (called an anticodon). When it connects the ribosome attaches the amino acid that tRNA was carrying to the polypeptide chain

10. ORDER MATTERS!
Order of DNA bases  order of RNA bases  order of amino acids  what protein is made
tRNA
Amino acid
mRNA

11. Transcription and Translation in plain English
Transcription and Translation Cell View

12. How to use the Codon Chart:
Use the left side to find the first letter in the codon
Use the top to find the second letter in the codon
Use the right side to find the third letter of the codon
Go to where ALL three overlap on the chart

14. How to use the Codon Wheel:
Begin in the middle with the first letter of the codon
Go outward to the second letter in the codon
Go outward again to the third letter in the codon.

15. Did you notice?: The codon “AUG” can specify methionine or serve as the “start” codon for protein synthesis.

16. What codon will tell the ribosome to quit putting amino acids together
What codon will tell the ribosome to quit putting amino acids together? What letters code for this?

17. Central Dogma Foldable
PG 48
Central Dogma Foldable

18. Save for a later date?
What is DNA? - Video

19. Codon Bingo! Directions For Playing:
If a codon (example: AAG) is called out, you must find the amino acid.
If an amino acid (example: serine) is called out, you must find the codon.
Hint! When finding a codon, there may be more than one answer…you can count all possible answers on your card!