1. The French Life Sciences Trend Analysis 2015

2. About Us The following statistical information has been obtained from Biotechgate. Biotechgate is a global, comprehensive, Life Sciences database encompassing the Biotechnology, Pharmaceutical and Medical Device industries. www.biotechgate.comwww.biotechgate.com The French Life Sciences Database is a part of the global Biotechgate and is brought to you in partnership with Alsace BioValley. www.frenchbiotech.com www.frenchbiotech.com Biotechgate is owned and operated by Venture Valuation AG, a Zurich based company specializing in independent assessment and valuation of technology-driven companies in high growth industries, such as the Life Sciences (Biotech, Pharma, Medtech), ICT, high-tech, Nanotech, Cleantech and Renewable energy. www.venturevaluation.comwww.venturevaluation.com

3. Overview of the French Life Science Industry 2015 Statistics Total Biotech Companies721 Medtech companies162 Pharma companies95 Investor companies22 Public / Non-Profit Organizations / Medical Facilities454 Other life science related companies499 Percentage of Publicly Owned Companies4% Life Sciences Venture Financing 2013 / 2014USD 209.2m / USD 143.4m Number of Technologies273 Licensing Opportunities336

4. Overview of the French Biotechnology Industry 2015 Statistics Total Biotech Companies721 Biotech - Therapeutics139 Biotech – R&D Services387 Biotech - Other195 Percentage of SME's87% Percentage of Publicly Owned Companies5.7% Biotech Venture financing 2013 / 2014USD 138.43m / USD 85.24m Licensing Opportunities221

5. Number of Employees

6. Company Ownership Life Science companies include Biotech, Medtech and Pharmaceutical companies.

7. Company Foundation Timeline

8. Key Activities of Biotechnology Companies

9. Biotech Products - Breakdown by Indication

10. Products in the Pipeline as of 07.10.2015

11. Biotechnology Financing in France – 5 year report H2 of 2015 includes data until 07.10.2015

12. Major Biotech Financing Rounds (2015) CompanySectorUSD M GenSight Biologics Biotech – Therapeutics & Diagnostics36.0 Genkyotex Innovation SAS Biotech – Therapeutics & Diagnostics21.7 InnaVirVax SA Biotech – Therapeutics & Diagnostics3.9

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14. Terms of Use The “French Life Sciences Trend Analysis” is based on data entered in the Biotechgate Database available at www.biotechgate.com. The statistics and graphs in this presentation are based on figures and information entered in this database and we do not guarantee any accuracy hereof. The use of the figures and graphs provided in this report is free of charge for any presentations as long as www.biotechgate.com is clearly cited as the source. For all other uses please contact us for terms and conditions. Biotechgate c/o Venture Valuation VV AG Kasernenstrasse 11 8004 Zurich Switzerland +41 (43) 321 86 60 www.venturevaluation.com