1. AP Biology: Big Idea #2 Glucose and regulation of metabolism
Metabolism Review
AP Biology:
Big Idea #2
Glucose and regulation of metabolism

2. Low calorie sweeteners?
How could they cause weight gain if they don’t add calories?
so-sweet-side-effects-of-artificial-sweeteners
Learning goals:
What is an opinion paper in a journal?
How does the brain regulate appetite?

3. Glucose Regulation Physiology challenge:
Volunteers from physiology to draw feedback loop:
Part of the loop that responds to digestion of candy from a psych bag.
Part of the loop that responds to forgetting to eat breakfast because you got up late and don’t want to miss your AP bio test!

5. Mechanism of insulin

6. Terms
Glycogen synthase
Glucagon
Gluconeogenesis

7. What actually causes? Stimulation of glucagon release?
Amino acids & low blood glucose
Inhibition of glucagon release?
Blood glucose & insulin
Stimulation of insulin release?
Glucose transported into beta cellchange in calcium levelsrelease of insulin granules
Inhibition of insulin release?
Presence of glucagon inhibits insulin release

8. Role of Dietary Fiber in Glucose and Cholesterol Regulation
Soluable Fiber
Forms a gel matrix
Inhibits absorption of fatty acids; lowers LDL
Inhibits absorption of glucose
Insoluable Fiber
Allows for movement of materials through digestive system
Fills you up and foods with high fiber tend to be less energy dense

9. Diabetes
Type 1
Type 2
Make a Venn Diagram to compare and contrast: cause, mechanism, and treatment for Type 1 and Type 2 diabetes.
Obesity Epidemic: In what ways is this medical issue a societal issue?

10. Diabetes Journal Club
Discussion of literature and understanding cause and treatments of Type 1 & Type 2 diabetes.
Prepare ahead of time!