1. Chapter 11 Cell Communication

2. Concept Check Questions Chapter 11 Cell Communication

3. Explain how nerve cells provide examples of both local and long- distance signaling. Chapter 11 Cell Communication

4. Explain how nerve cells provide examples of both local and long- distance signaling. Synapse = local Electrical = long distance Chapter 11 Cell Communication

5. Nerve growth factor (NGF) is a water-soluble signal molecule. Would you expect the receptor for NGF to be intracellular or in the plasma membrane? Why? Chapter 11 Cell Communication

6. Nerve growth factor (NGF) is a water-soluble signal molecule. Would you expect the receptor for NGF to be intracellular or in the plasma membrane? Why? Hydrophylic Chapter 11 Cell Communication

7. What is a protein kinase, and what is its role in a signal transduction pathway? Chapter 11 Cell Communication

8. What is a protein kinase, and what is its role in a signal transduction pathway? A protein that phosphorylates another protein, often in a cascade. Chapter 11 Cell Communication

9. When a signal transduction pathway involves a phosphorylation cascade, how does the cell’s response get turned off? Chapter 11 Cell Communication

10. Protein kinase = on Protein phosphatase = off Chapter 11 Cell Communication

11. Upon activation of phospholipase C by ligand binding to a receptor, what effect does the IP 3 -gated calcium channel have on Ca 2+ concentration in the cytosol? Chapter 11 Cell Communication

12. Gate opens. Ca ++ flows out of ER. [Ca ++ ] goes up. Chapter 11 Cell Communication

13. How can a target cell’s response to a hormone be amplified more than a millionfold? Chapter 11 Cell Communication

14. How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

15. How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

16. How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

17. How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

18. How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

19. Explain how two cells with different scaffolding proteins could behave differently in response to the same signaling molecule. Chapter 11 Cell Communication