1. Nano to go Raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow Federal Institute for Occupational Safety and Health (BAuA, Ger) 8th EU/US Joint Conference on Health and Safety at Work Fort Worth, Texas, 17 – 19 September 2016

2. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Practical guideline: Nano to go! (BAuA, 2015) field measurement reports: expert assessment of safety and health at different workplaces, combining measurements and non- measurement methods all available for download: www.baua.de/nanoToGo 2

3. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Nano-to-go guidance for workplace risk management based on the EU CAD directive (98/24/EC) Target groups: material scientists in universities, reseach institutes, startups health and safety professionals, HSE manager in SME OSH inspectors 3

4. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Manual Nano to Go!  Contains a brochure, a flyer and a USB stick  USB stick: ‒Brochure ‒Seven presentations ‒Four field studies ‒Six supplementary documents available for download www.baua.de/nanoToGo www.nanosafetycluster.eu/nanoToGo www.nanovalid.eu/nanoToGo 4

5. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Brochure: Guidance for Risk Management 5

6. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Field studies Silica-particles in pilot plant CNTs in pilot plant ZnO-particles in laboratory CNTs in laboratory 1 2 34 pics: 1 - Christof Asbach (IUTA), 2 and 4 – nanofibre test center (BAuA), 3 - Aart Rouw (BAuA) 6

7. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Slides for information and training  The complex world of nanomaterials  Basics of nanotoxicology  Information gathering  Risk assessment and efficiency control  Derivation of control strategies  Ways to approach nanomaterial toxicology  Basics on chemical regulation 7

8. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Supplementary documents  Short introductory view on “Safety Management and Nano Material”  Operating instruction (blank form and example)  Sampling protocol (blank form)  Dialogue guide – questions for field studies (blank form)  SOP for laboratory practice (example) 8

9. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Praktical guidelines for nanomaterials at work (2014) employers, health and safety professionals workers follows a control banding approach for risk management „NANO TO GO“ for start-ups and research institutions in material science (2015) Guidance based on the EU Chemical Agents Directive 98/24/EC N 9

10. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 BAuA research agenda 2020: Advanced materials concepts und methods for an early detection of hazards and risks prinziples for „safety by design" adequate OSH in an early stage of material innovation build-up of a systematic consultation of institutions and start-up enterprises in material science safe and sustainable development approved safe and standardised working procedures adaption of REACH information and testing requirements to health risks from respirable biopersistent particles good information along supply chains safe use in life-cycle 10

11. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Application safety of advanced materials and products safe material design to avoid hazardous properties direct application safety safe product design to avoid release of particles integrated application safety safe workplace design to avoid health and environmental risks supported application safety 11

12. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 http://doc.utwente.nl/95996/1/thesis_A_Reichow.pdf How can we support start-ups in the development of safe and sustainable advanced materials? Good Governance needs trust → Collaboration in governance-networks sharing resources generating new knowledge developing rules for the safe development of (certain) nanomaterials 12

13. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Existing networks Individual actors (Start-ups, scientists, regulators etc.) Setting up new network (BAuA as central „network manager“) Proposal for a supporting structure for the safe and sustainable development of nano-scale and other advanced materials Evaluation Project start: November 2015 Duration (initially): 4 years Project aims: Develop robust concept in form of supporting structure for startups: 1. prepare fulfilling relevant legal obligations (REACH, OSH) 2. enable contribution to regulatory process (“soft” to “hard(ened)” regulation → legal certainty) 13

14. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Projects “Safe nanocarbons“ in-vivo studies on selected advanced nanocarbons (SWCNT, MWCNT, CNH, graphene,...) Mode of toxic action of nanocarbons (started, 2015 – 18) i.a. improvement of new methods for determination of fibre rigidity Dustiness and particle morphology of nanocarbons (started, 2015 – 2018) Determination of potential for release and toxicological assessment of respirable particles and fibres in different working processes Safety in life-cycle of nanocarbons (planned) Proposal for an amendment of current recommendation BekGS 527 „Manufactured nanomaterials“, i.a. „nanocarbon map“, „risk matrix“ Risk management map for handling nanocarbons at the workplace (planned) 14

15. Nano to go: raising awareness in material science and startup enterprises Dr. Rolf Packroff, Dr. Aart Rouw, Dr. Aline Reichow 8 th EU-US Joint Conference on Health and Safety at Work, Fort Worth, 2015 Thank you for your attention! Subsequent questions: Nanovalid@baua.bund.de More informations: www.baua.de/de/nanotechnology www.baua.de/de/nanotechnology 15