1. Global Advocacy and TReND in Africa

2. Research training Research facilities Cost- effective model systems Open source Skills transfer programme Outreach

3. Research training Intensive practical-based schools: IBRO school on insect neuroscience and Drosophila neurogenetics (Uganda & Tanzania) – 4 th just finished TReND school on molecular biology of brain ageing (Mekelle, Ethiopia) – 1 st just finished TReND-ICIPE school on bio-informatics (Nairobi, Kenya) – Calls open, November 2014 TReND school on “How to build your own equipment with open source resources” (Addis Ababa, Ethiopia) – Planning for 2015 Human brain imaging and behavioural neuroscience course – being planned

4. Equipment donations paired with short visits from experts upon request from partner Universities Support research facilities and Skills transfer programme

5. Support research facilities and Skills transfer programme Important equipment donated so far to Universities in Uganda, Ethiopia, Tanzania and Nigeria

6. Optimising resources Use of cost-effective model organisms State-of-the-art genetics in Drosophila, Anopheles, Aedes Physiology methods in bees, grasshopers and crickets

7. Tom Baden Open Hardware Hardware Thomas.baden@uni-tuebingen.de

8. Science is expensive!

10. Open Source Software

11. Open Source Hardware! (partly)

12. Mini-“computers“ & microcontrollers ~$50-100 ~$35 ~$30

13. Desktop 3D printers ~$2-4k ~$250-500 RepRap Replicator2

14. Some open hacks for lab equipment Hackateria.org Sterilisation hood PCR Extracellular Amp Backyard brains

15. This is not a niche market! Pearce 2012, Science

16. Fully motorised micromanipulator http://trendinafrica.org/activities/open-source

17. Pipettes http://trendinafrica.org/activities/open-source

18. PhoneScope

19. http://trendinafrica.org/activities/open-source Key: Customizabililty

20. http://trendinafrica.org/activities/open-source Key: Customizabililty

21. Thingiverse – lots of free lab-designs

22. Survey amongst African academics Computer Literacy Never heard No access Have tried Routine user Open Hardware lowhigh N = 77 responses, 10 African countries, 23 Universities

23. http://trendinafrica.org/activities/open-source Leveraging Open Hardware

24. http://trendinafrica.org/activities/education Leveraging Open Hardware

25. Teaching how to improvise http://trendinafrica.org/activities/education Chinese chop sticks Webcam

26. Teaching how to improvise http://trendinafrica.org/activities/education Mobile phone camera ~10*9V Batteries in series to power the gel

27. Open Neuroscience A.M. Chagas http://openeuroscience.wordpress.com/

28. Some upcoming events University of Addis Abeba, Ethiopia Workshop “How to build your own lab- equipment“ A M Chagas and T Baden ICIPE, Nairobi, Kenya Workshop “Open Source tools in Bioinformatics“, Funding obtained! J Aleksic University of Addis Abeba, Ethiopia Workshop “How to build your own lab- equipment“, Grant submitted Crowdfunding campaign to establish a permanent 3D printing facility at Dar es Salaam International University P Parslow, L Prieto, T Baden et al. http://trendinafrica.org/activities/education

29. Applications open now University of Dar es Salaam, Tanzania 3rd IBRO school on Insect neuroscience and Drosophila Neurogenetics. Aug 2014 T Baden, S Yusuf, F Stephano, L Prieto http://trendinafrica.org/activities/education

30. Acknowledgements

31. Outreach Outreach to students and teach-the-teachers at primary and secondary schools as well as Universities and general public in Nigeria, Ghana, Uganda, and Tanzania Fight stigmas on brain diseases with education Mega-outreach during Brain Awareness week Press coverage – Nigerian National TV Attracted international funding – Wellcome Trust Run by TReND alumni using open source equipment

32. How?

33. Suggestions for effective brain research advocacy in Africa Governments Universities Industry -Campaign to raise sciences status -More funding for basic research -Promote IT literacy -Less teaching for researchers -Improve teaching methods- critical thinking -Encourage public outreach -More communication -Increase partnerships with university researchers -Train local technicians to maintain equipment

34. Summer schools www.trendinafrica.org We share 60% of our DNA 70% of known human disease genes have Drosophila counterparts. Inexpensive to bread Easy to transport Friendly community Genetic tools!!! Why flies?

35. Outcome 2011 Course survey (took into account for second course)

36. Outcome 2011 Course survey (took into account for second course)

37. Outcome 2011 Course survey (took into account for second course)

38. Neuroscience MSc course at KIU -Take the syllabus from Tuebingen University and adjust it to suit teaching capacity at KIU -Will be taught by local faculty when expertise is available, international faculty will fly in for short intensive courses, and on line teaching will be implemented to complement the teaching experience -Plan approved by the educational council in Uganda -In co-ordination with Tuebingen grad school for Neuroscience.