1. Chapter 5 Bulk Transport Local and Long Distance Signaling

2. You Must Know Bulk Transport How cells communicate with each other.

3. CONCEPT 5.5: Bulk transport across the plasma membrane occurs by exocytosis and endocytosis Exocytosis © 2014 Pearson Education, Inc. Endocytosis

4. CONCEPT 5.6: The plasma membrane plays a key role in most cell signaling In multicellular organisms, cell-to-cell communication allows the cells of the body to coordinate their activities. Communication between cells is also essential for many unicellular organisms. © 2014 Pearson Education, Inc.

5. Local Signaling By Direct Contact

6. Plant Cells Local Signaling By Direct Contact

7. Local regulator diffuses through extracellular fluid. Secreting cell Secretory vesicle Target cell Local signaling Paracrine signaling Ex. Growth Factors

8. Target cell is stimulated. Electrical signal along nerve cell triggers release of neuro- transmitter. Neurotransmitter diffuses across synapse. Synaptic signaling Local signaling © 2014 Pearson Education, Inc.

9. Long-distance signaling Endocrine cell Target cell specifically binds hormone. Endocrine (hormonal) signaling Hormone travels in bloodstream. Blood vessel © 2014 Pearson Education, Inc.