2. Large Intestine Slide 14.28 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Larger in diameter, but shorter than the small intestine  Frames the internal abdomen

3. Large Intestine Slide 14.28 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.8

4. Functions of the Large Intestine Slide 14.29 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Absorption of water  Eliminates indigestible food from the body as feces  Does not participate in digestion of food  Goblet cells produce mucus to act as a lubricant

5. Structures of the Large Intestine Slide 14.30a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Cecum – saclike first part of the large intestine  Appendix  Accumulation of lymphatic tissue that sometimes becomes inflamed (appendicitis)  Hangs from the cecum

6. Structures of the Large Intestine Slide 14.30b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Colon  Ascending  Transverse  Descending  S-shaped sigmoidal  Rectum  Anus – external body opening

7. Structures of the Large Intestine Slide 14.30b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Colon  Ascending  Transverse  Descending  S-shaped sigmoidal  Rectum  Anus – external body opening

8. Food Breakdown and Absorption in the Large Intestine Slide 14.61 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  No digestive enzymes are produced  Resident bacteria digest remaining nutrients  Produce some vitamin K and B  Release gases  Water and vitamins K and B are absorbed  Remaining materials are eliminated via feces

9. Propulsion in the Large Intestine Slide 14.62 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Sluggish peristalsis  Mass movements  Slow, powerful movements  Occur three to four times per day  Presence of feces in the rectum causes a defecation reflex  Internal anal sphincter is relaxed  Defecation occurs with relaxation of the voluntary (external) anal sphincter

10. Accessory Digestive Organs Slide 14.32 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Salivary glands  Teeth  Pancreas  Liver  Gall bladder

11. Salivary Glands Slide 14.33 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Saliva-producing glands  Parotid glands – located anterior to ears  Submandibular glands  Sublingual glands

12. Saliva Slide 14.34 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Mixture of mucus and serous fluids  Helps to form a food bolus  Contains salivary amylase to begin starch digestion  Dissolves chemicals so they can be tasted

13. Teeth Slide 14.35a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  The role is to masticate (chew) food  Humans have two sets of teeth  Deciduous (baby or milk) teeth  20 teeth are fully formed by age two

14. Teeth Slide 14.35b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Permanent teeth  Replace deciduous teeth beginning between the ages of 6 to 12  A full set is 32 teeth, but some people do not have wisdom teeth

15. Classification of Teeth Slide 14.36a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Incisors  Canines  Premolars  Molars

16. Classification of Teeth Slide 14.36b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.9

17. Regions of a Tooth Slide 14.37a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Crown – exposed part  Outer enamel  Dentin  Pulp cavity  Neck  Region in contact with the gum  Connects crown to root Figure 14.10

18. Regions of a Tooth Slide 14.37b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Root  Periodontal membrane attached to the bone  Root canal carrying blood vessels and nerves Figure 14.10

19. Pancreas Slide 14.38 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Produces a wide spectrum of digestive enzymes that break down all categories of food  Enzymes are secreted into the duodenum  Alkaline fluid introduced with enzymes neutralizes acidic chyme  Endocrine products of pancreas  Insulin  Glucagons

20. Digestive enzymes digest proteins trypsin, chymotrypsin digest starch amylaseBuffers neutralizes acid from stomach Pancreas

21. Liver Slide 14.39 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Largest gland in the body  Located on the right side of the body under the diaphragm  Consists of four lobes suspended from the diaphragm and abdominal wall by the falciform ligament  Connected to the gall bladder via the common hepatic duct

22. Bile Slide 14.40 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Produced by cells in the liver  Composition  Bile salts  Bile pigment (mostly bilirubin from the breakdown of hemoglobin)  Cholesterol  Phospholipids  Electrolytes

23. Role of the Liver in Metabolism Slide 14.77 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Several roles in digestion  Detoxifies drugs and alcohol  Degrades hormones  Produce cholesterol, blood proteins (albumin and clotting proteins)  Plays a central role in metabolism

24. Gall Bladder Slide 14.41 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Sac found in hollow fossa of liver  Stores bile from the liver by way of the cystic duct  Bile is introduced into the duodenum in the presence of fatty food  Gallstones can cause blockages

25. Processes of the Digestive System Slide 14.42a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Ingestion – getting food into the mouth  Propulsion – moving foods from one region of the digestive system to another

26. Processes of the Digestive System Slide 14.42b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Peristalsis – alternating waves of contraction  Segmentation – moving materials back and forth to aid in mixing Figure 14.12

27. Processes of the Digestive System Slide 14.43 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Mechanical digestion  Mixing of food in the mouth by the tongue  Churning of food in the stomach  Segmentation in the small intestine

28. Processes of the Digestive System Slide 14.44 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Chemical Digestion  Enzymes break down food molecules into their building blocks  Each major food group uses different enzymes  Carbohydrates are broken to simple sugars  Proteins are broken to amino acids  Fats are broken to fatty acids and alcohols

29. Processes of the Digestive System Slide 14.45 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Absorption  End products of digestion are absorbed in the blood or lymph  Food must enter mucosal cells and then into blood or lymph capillaries  Defecation  Elimination of indigestible substances as feces

30. Processes of the Digestive System Slide 14.46 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.11

31. Control of Digestive Activity Slide 14.47a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Mostly controlled by reflexes via the parasympathetic division  Chemical and mechanical receptors are located in organ walls that trigger reflexes

32. Control of Digestive Activity Slide 14.47b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Stimuli include:  Stretch of the organ  pH of the contents  Presence of breakdown products  Reflexes include:  Activation or inhibition of glandular secretions  Smooth muscle activity

33. Nutrition - Take a Class! Slide 14.63 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Nutrient – substance used by the body for growth, maintenance, and repair  Categories of nutrients  Carbohydrates: simple sugars, starches, fiber  Lipids: triglycerides, phospholipids, fatty acids  Proteins: amino acids  Vitamins  Mineral  Water

34. Body Energy Balance Slide 14.83 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Energy intake = total energy output (heat + work + energy storage)  Energy intake is liberated during food oxidation  Energy output  Heat is usually about 60%  Storage energy is in the form of fat or glycogen