1. 5 4 Number your bellwork 1 - 6, and fill in the missing blanks. Human cells have 46 chromosomes. After the cell cycle is complete, each daughter cell is genetically identical, both daughter cells contain how many chromosomes? 46 1 2 3 Chromosome 6

2. Collect Today Cell Cycle/Vocabulary Quiz Page 58 – Cell Cycle Foldable Assigned Notecard Definitions (Due TOMORROW) Late Page 59 – Cell Cycle Concept Map (-30%) Page 56 – Interphase Handout (-50%)

3. Unit 4 – Cell Cycle Definitions Due Friday (11/6/15) All Parts Due Friday (11/13/15) 1.Allele 2.Anaphase 3.Cancer 4.Cell Cycle 5.Centriole 6.Centromere 7.Chromatid 8.Chromosome 9.Crossing Over 10.Cytokinesis 11.Daughter Cell 12.Diploid 13.Electrophoresis 14.Frameshift Mutation 15.Gamete 16.Gene 17.Genetic Disorder 18.Genome 19.Haploid 20.Interphase 21.Karyotype 22.Meiosis 23.Metaphase 24.Mitosis 25.Mutation 26.Offspring 27.Point Mutation 28.Prophase 29.Sexual Reproduction 30.Somatic 31.Telophase 32.Tumor Pg 54

4. Youtube How do cancer cells behave differently from healthy ones? - George Zaidan

5. Essential Question What is uncontrollable cell division? Standard B.5D – Recognize that disruptions of the cell cycle lead to diseases such as cancer Pg 55

6. Cancer is a disorder in which some of the body’s own cells lose the ability to control growth.

7. Cancer cells do not respond to the signals that regulate the growth of most cells. Cancer cells divide uncontrollably and form masses of cells called tumors. Tumors are harmful because they damage surrounding tissues.

8. Cancer cells may break loose from tumors and spread (metastasis) throughout the body.

9. Cancer may be caused by tobacco, radiation, or viral infection. All cancers have one thing in common: The control over the cell cycle has broken down.

10. A large number of cancer cells have a defect in the p53 gene. The p53 gene normally halts the cell cycle until all chromosomes have been replicated.

11. Cancer Research Activity Today, you will learn about one of the most prevalent medical concerns of our time. You will learn the basics of what cancer is. Use the steps below to get to the site where you will find your information. Answer the questions in complete sentences. Part A Watch the video about cancer and answer the questions. “The Cell Cycle and Cancer” by the Amoeba Sisters on YouTube. http://youtu.be/lpAa4TWjHQ4 http://youtu.be/lpAa4TWjHQ4 Part B Go to the following site: www.cancer.orgwww.cancer.org Click on the link labeled “Learn about Cancer” in the top left of the page. Click on the link labeled “Cancer Basics” on the right side of the page under the “Learn about cancer topics”. Click on the “What is Cancer?” tab under the “Understanding Cancer” Section. Pg 60