1. Summary of “Fecal Worm Egg Count Reduction” Trials in Merck Animal Health National Data Base
Donald H. Bliss1
Robert D. Moore2
William G. Kvasnicka3
1MidAmerica Ag Research, Verona, WI
2College of Agriculture, Biotechnology & Natural Resources, University of Nevada
3University of Nevada, Professor Emeritus

2. Protocol for Fecal Worm Egg Count Reduction Test (FECRT)
All clinics agreed to use a standard protocol:
20 samples taken at the time of treatment.
20 samples taken 14-days after treatment.
Pre-/post-treatment samples sent to same lab:
● Treatment not revealed until test completed.
● Modified WI Sugar Flotation Technique (Eggs/3 g).
● Results sent to participating clinic and entered
in Merck Animal Health National Database.

3. Fecal Egg Count Reduction Test Results
250+ Participating Vet Clinics.
24+ States Represented.
580+ Trials Completed.
19,996 Samples Analyzed.
10,069 Pre-treatment Samples.
9,927 Post-treatment Samples.

4. Table 1: Efficacy Summary for Fecal Egg Count Reduction Test Conducted with Macocyclic Lactone Endecticide Pour-On Products ( ).
_________________________________________________________________ No. of No. of Egg Counts/3g* Percent
Products Trials Samples Pre-Rx Post-Rx Efficacy(%)
Pour-ons:
Ivomec® PO %
Ivermectin PO , %
Dectomax® PO %
Cydectin® PO %
Eprinex® PO %
PO Summary , %
_________________________________________________________________
*All samples taken at Rx and again 14-days post-Rx.
**Updated Jan. 3, 2013

5. No. of No. of Egg Counts/3g* Percent
Table 2: Efficacy Summary for Fecal Egg Count Reduction Test Conducted with Injectable Macrocylic Lactone Endecticide Products ( ).
__________________________________________________________________________________
No. of No. of Egg Counts/3g* Percent
Products Trials Samples Pre-Rx Post-Rx Efficacy
Injections:
Ivomec® Inj %
Ivomec® Plus %
Dectomax® Inj %
Cydectin Inj %
Ivermectin Inj %
Generic Ivo Plus %
Inj. Summary: , %
_____________________________________________________________
*All samples taken at Rx and again 14-days post-Rx.
**Updated Jan. 3, 2013

6. Table 3: Efficacy Summary for Fecal Egg Count Reduction Test Conducted with Various Safe-Guard® & Panacur® Formulations.
______________________________________________________________________________________
No of No of Egg Counts/3g* Percent
Products Trials Samples Pre-Rx Post-Rx Efficacy
Panacur® Drench , %
SG Drench/Paste , %
Summary-Drench , %
SG Feed/1.96% , %
SG Mineral %
Liquid Feed %
Cubes/blocks/Paste %
Overall Summary** , %
________________________________________________________________
* All samples taken at Rx and again 14-days post-Rx – Updated Jan. 3, 2013.
** Note: Coccidia prevalence was reduced by 56.5%.

7. Table 4: Efficacy Summary for Fecal Egg Count Reduction Test Conducted with Safe-Guard®/ Panacur® in Combination with Various Endecticide Formulations.
_____________________________________________________________________________________
Combination No of No of Egg Counts/3g Percent
Product Trials Samples Pre-Rx Post-Rx Efficacy
Safe-Guard® or Panacur ® plus:
Ivomec® Inj./plus/PO %
Ivermectin PO/Inj , %
Dectomax® Inj./PO %
Cydectin PO %
Combination , %
Summary
_______________________________________________________
Note: Coccidia prevalence was reduced by 76.9% *Updated Jan. 3, 2013

8. Table 5: Efficacy Summary for Fecal Egg Count Reduction Test Conducted for all Products.
______________________________________________________________________________________
Number of Number of Egg Counts/3g** Percent
Products Trials Samples Pre-Rx Post-Rx Efficacy(%)
Endecticide
Injectable: , %
Pour-On: , %
Safe-Guard®
/Panacur® , %
Combination
Treatment*** , %
______________________________________________________________________
*Updated Jan. 3, 2013, **All samples taken at Rx and 14-days post-Rx.
*** Safe-Guard® plus an Endecticide.

9. Table 6: Comparison of FECRT Efficacy for ML Pour-Ons 2008(AABP) vs
Table 6: Comparison of FECRT Efficacy for ML Pour-Ons 2008(AABP) vs. 2013(Jan. 3)
Products No. of Trials Percent No. of Trials Percent Efficacy Efficacy Efficacy Change
Ivomec® % % %
Ivermectin % % %
Dectomax® % % %
Cydectin® % % %
Summary % % %
Updated Jan. 3, 2013

10. Table 7: Comparison of FECRT Efficacy ML Injectables: 2008(AABP) vs
Table 7: Comparison of FECRT Efficacy ML Injectables: 2008(AABP) vs. 2013(Jan. 3)
Products No. of Trials Percent No. of Trials Percent Efficacy Efficacy Efficacy Change
Ivomec® Inj % % %
Ivomec® Plus % % %
Ivermectin or
Ivermectin plus % % %
Dectomax® % % %
Cydectin® % % %
Summary % % %
Updated January 3, 2013