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Evaluating Outcomes for Clients with Thyroid and Parathyroid Problems

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1 Evaluating Outcomes for Clients with Thyroid and Parathyroid Problems

2 The thyroid gland contains spherical follicles (50–500 μmin diameter).
Follicle cells synthesize the two iodine-containing thyroid hormones thyroxine (T4, tetraiodothyronine) and triiodothyronine (T3).

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5 PARATHYROID GLAND Location: Usually paired.
Very small (less than 5 mm). Called parathyroid glands because of their position on posterior margins outer surface of thyroid gland. More superior of each pair usually near middle of margin of lobe. More inferior of each pair usually at inferior apex of lobe. Function: PARATHYROID HORMONE (PTH) – raises the level of calcium in the blood, decreases levels of blood phosphate. Partially antagonistic to calcitonin of thyroid gland.

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10 Thyroid hormone activation of target cells

11 Hyperthyroidism Thyrotoxicosis
Graves’ disease, the most frequent causes: goiter, exophthalmos, pretibial myxedema Laboratory assessment Thyroid scan Ultrasonography Electrocardiography

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14 Drug Therapy Radioactive iodine therapy; not used in pregnant women
Additional drug therapy may be needed. Implement radiation precautions. Monitor regularly for changes in thyroid function. S&P

15 Surgical Management Surgery possible in absence of good response to drug therapy. Postoperative care for: Hemorrhage Respiratory distress Hypocalcemia and tetany Laryngeal nerve damage Thyroid storm or thyroid crisis

16 Infiltrative Opthalmopathy
Provide symptomatic treatment. Treatment of hyperthyroidism does not correct eye and vision problems of Graves’ disease. Elevate the head of bed at night. Instill artificial tears. Treat photophobia with dark glasses. S&P

17 Hypothyroidism Decreased metabolism from low levels of thyroid hormones Myxedema coma a rare, serious complication Mostly a result of thyroid surgery and radioactive iodine treatment of hyperthyroidism Clinical manifestations S&P

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20 Decreased Cardiac Output
Interventions: Monitor circulatory status. Monitor for signs of inadequate tissue oxygenation. Monitor for changes in mental status. Monitor fluid status and heart rate. Administer oxygen or mechanical ventilation, as appropriate.

21 Ineffective Breathing Pattern
Interventions: Observe and record rate and depth of respirations. Auscultate the lungs. Assess for respiratory distress. Assess the client receiving sedation for respiratory adequacy.

22 Disturbed Thought Processes
Interventions: Assess lethargy, drowsiness, memory deficit, poor attention span, and difficulty communicating. These problems should decrease with thyroid hormone treatment. Provide a safe environment. Provide family teaching. S&P

23 Myxedema Coma Coma, respiratory failure, hypotension, hyponatremia, hypothermia, hypoglycemia Emergency care

24 Thyroiditis Inflammation of the thyroid gland
Three types of thyroiditis: acute, subacute (granulomatous), and chronic (Hashimoto’s disease)—the most common type Dysphagia and painless enlargement of the gland Nonsurgical management, drug therapy Surgical management

25 Thyroid Cancer Papillary, follicular, medullary, and anaplastic
Collaborative management Surgery treatment of choice: thyroidectomy Suppressive doses of thyroid hormone for 3 months after surgery Study performed after drugs are withdrawn S&P

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27 Hyperparathyroidism Parathyroid glands: calcium and phosphate balance
Hypercalcemia and hypophosphatemia Nonsurgical management: Diuretic and fluid therapy Drug therapy: phosphates, calcitonin, calcium chelators S&P

28 Surgical Management Parathyroidectomy preoperative care:
Client stabilized; calcium levels normalized Studies: bleeding and clotting times, CBC Teaching: coughing, deep-breathing exercises, neck support Operative procedures (Continued) S&P

29 Surgical Management (Continued)
Postoperative care includes: Observe for respiratory distress. Keep emergency equipment at bedside. Hypocalcemic crisis can occur. Recurrent laryngeal nerve damage can occur.

30 Hypoparathyroidism Decreased function of the parathyroid gland
Iatrogenic hypoparathyroidism Idiopathic hypoparathyroidism Hypomagnesemia Interventions: correcting hypocalcemia, vitamin D deficiency, and hypomagnesemia

31 If a manifestation is caused by hyperthyroidism, indicate “HYPER”
If a manifestation is caused by hyperthyroidism, indicate “HYPER”. If a manifestation is caused by hypothyroidism, indicate “HYPO.” Decreased body temperature Palpitations Apathy Diaphoresis Thinning of scalp hair Thick, brittle nails Constipation Tremors Heat intolerance Weight gain Tachycardia Insomnia Dry, coarse, brittle hair Decreased activity tolerance

32 HYPO = Hypothyroidism HYPER = Hyperthyroidism
Tremors: HYPER Heat intolerance: HYPER Weight gain: HYPO Tachycardia: HYPER Insomnia: HYPER Dry, coarse, brittle hair: HYPO Decreased activity tolerance: HYPO Decreased body temperature: HYPO Palpitations: HYPER Apathy: HYPO Diaphoresis: HYPER Thinning of scalp hair: HYPER Thick, brittle nails: HYPO Constipation: HYPO

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