1. The Cell Membrane Cell Membrane Properties

2. In or Out? How is a window screen similar to a cell membrane? –What are some things that can pass through a window screen? –What are some things that can not pass through a window screen? Why is it important to keep these things from moving through the screen? –Why is it important to regulate what moves into and out of the cell?

3. Main part of the cell membrane Phospholipid  mainly lipid molecule that contains phosphate

4. Composition (make-up) of cell membrane hydrophobic lipid tail Hydrophilic phosphate head Lipid bilayer Protein channel Carbohydrate chain glycoprotein

5. Properties and Composition Vocabulary Selectively permeable: allows only certain things to enter Lipid Bilayer: Double layered structure composed of lipids, proteins, and carbohydrates Hydrophobic lipid tails: Fatty acid tails stay away (inside) from cytoplasm “water fearing” Hydrophilic phosphate heads: face the cytoplasm “ water loving” Integral Protein Channel: passageway for large molecules to enter and leave cell Peripheral Glycoproteins: proteins that act as receptors to receive chemical messages from the outside of the membrane Carbohydrate Chains: can receive certain molecules into cell by means of a receptor

6. Complete Cell Membrane

7. Main Function of the Cell Membrane Regulates what molecules enter in and out of the cell to help maintain the HOMEOSTASIS of the cell

8. How Do Molecules Pass Through the Membrane? Passive Transport Active Transport

9. Diffusion- A type of passive transport

10. DIFFUSION Does NOT require energy Occurs when there is a concentration GRADIENT –Gradient: a difference in amounts. Gradients move from high to low DIFFUSION GOES WITH THE GRADIENT HIGH CONCENTRATION  LOW CONC. Molecules will stop diffusing when they are equal on both sides of the membrane Oxygen and carbon dioxide use this method of transport through the membrane http://highered.mcgraw- hill.com/sites/0072495855/student_view0/chapter2/animation__how _diffusion_works.htmlhttp://highered.mcgraw- hill.com/sites/0072495855/student_view0/chapter2/animation__how _diffusion_works.html

11. Facilitated Diffusion Facilitate= help No energy is required helped by a protein channel Proteins channels have larger openings so that larger molecules diffuse through the membrane Moves with the gradient HIGH  LOW CONCENTRATION

13. Click to view the animation about facilitated diffusion http://highered.mcgraw- hill.com/sites/0072495855/student_view0/ chapter2/animation__how_facilitated_diffu sion_works.htmlhttp://highered.mcgraw- hill.com/sites/0072495855/student_view0/ chapter2/animation__how_facilitated_diffu sion_works.html

14. Passive Transport

15. Active Transport –Requires ATP (cellular energy) –Movement of molecules AGAINST the concentration gradient –Movement of molecules from Low concentration  High concentration Sodium and Potassium pump is an example of how nerve cells maintain a high concentration of sodium on one side

16. Click to view the animation of active transport http://highered.mcgraw- hill.com/sites/0072495855/student_view0/ chapter2/animation__how_the_sodium_po tassium_pump_works.htmlhttp://highered.mcgraw- hill.com/sites/0072495855/student_view0/ chapter2/animation__how_the_sodium_po tassium_pump_works.html

17. HIGH LOW ENERGY FROM ATP PUSHES MOLECULES ACROSS THE MEMBRANE

18. WATCH ACTIVE TRANSPORT LOW TO HIGH ENERGY NEEDED

19. Active Transport

20. TYPES OF ACTIVE TRANSPORT Endocytosis: molecules moving INTO the cell. – Phagocytosis: large particles are ingested into the cell –Pinocytosis: When solutes are taken into the cell Exocytosis: molecules moving OUT of the cell THESE ALL REQUIRE ENERGY (ATP)

21. Phagocytosis Animation http://highered.mcgraw- hill.com/sites/0072495855/student_view0/ chapter2/animation__phagocytosis.htmlhttp://highered.mcgraw- hill.com/sites/0072495855/student_view0/ chapter2/animation__phagocytosis.html

22. Endocytosis Exocytosis

23. How Do Certain Factors Affect How Molecules Move Through the Membrane? Molecule size  smaller molecules move faster through than larger through membrane Charge on molecule  outside of membrane is attracted to polar molecules inside to nonpolar molecules Concentration of molecules  more molecules on one side of the membrane will affect rate which movement happens Temperature of Cellular Environment: molecules move quicker in warmer temps slower in cooler temp

24. The Tea Bag Demo Imagine the tea bag is the cell. The contents inside are the organelles. The bag itself is the membrane. Place the tea bag in room temp water. Notice the rate at which the water changes color which is an indication of molecule movement. Place the second tea bag in the warm/hot water. Notice the difference that it makes