1. 1 Dr Gary Wills, Project Lead, The University of Southampton Dr Simon Grange, RNOH, Orthapedic Surgeon Mike Santer, Project Manager, The University of Southampton

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3. What are the issues being addressed? Changes in Governance requirements for medical translational research Auditable adherence to NHS and MRC trial processes Communication within and across project teams Clinical data capture and reuse 3

4. How? A previously funded JISC VRE project called CORE (collaborative Orthopaedic Research Environment) has explicitly tackled these issues, and so the aim of this project is to take the CORE VRE, embed it into the RNOH Solution built on open framework (DJANGO) 4

5. Trial Protocol Definition Clinical Data Audited Governance 5 Student Trial Random Control Trial Clinical Audit

6. Current RNOH Projects using VRIC Surface EMG - Dana Maki - 'Scenario prototyping' - Demonstrating data capture techniques, governance and documentation recording 'Brake Pedal' - Kirsty MacLeod - 'Horizontal prototype' demonstrating Basic Science -> Clinical and Ethics preparation, plus multicentre work Clinical Databases - Raphael Malikian - These are for supporting the paediatric, shoulder and part of the spinal service demonstrating the 'vertical prototype' of data capture from the clinical level. 6

7. Future Trails 10 more projects starting in April that will use VRIC Further discussions with MRC in London and Cape Town, South Africa in April Consortium - European Union http://www.nanobridge.eu/converis/ 7

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13. Future Work Procedural Case Study Technical Case Study Support Documentation Web2.0 Features 13

14. 14 VRIC Sites: Blog: http://blogs.ecs.soton.ac.uk/vric/http://blogs.ecs.soton.ac.uk/vric/ Website: http://www.vric.ecs.soton.ac.uk/http://www.vric.ecs.soton.ac.uk/ WIKI: http://wiki.vric.ecs.soton.ac.uk/index.php/Main_Page http://wiki.vric.ecs.soton.ac.uk/index.php/Main_Page DevSite: http://lslvm-jc1.ecs.soton.ac.uk/trials/http://lslvm-jc1.ecs.soton.ac.uk/trials/ Contact: Mike Santer The University of Southampton, ECS mhds@ecs.soton.ac.uk VRIC Sites: Blog: http://blogs.ecs.soton.ac.uk/vric/http://blogs.ecs.soton.ac.uk/vric/ Website: http://www.vric.ecs.soton.ac.uk/http://www.vric.ecs.soton.ac.uk/ WIKI: http://wiki.vric.ecs.soton.ac.uk/index.php/Main_Page http://wiki.vric.ecs.soton.ac.uk/index.php/Main_Page DevSite: http://lslvm-jc1.ecs.soton.ac.uk/trials/http://lslvm-jc1.ecs.soton.ac.uk/trials/ Contact: Mike Santer The University of Southampton, ECS mhds@ecs.soton.ac.uk