1. MEIOSIS By Diana Bivens

2. Meiosis vs. Mitosis Mitosis: period of nuclear division in which two daughter cells are formed, each identical to the parent cell Mitosis: period of nuclear division in which two daughter cells are formed, each identical to the parent cell

3. Meiosis vs. Mitosis Meiosis: type of division in which four cells are formed, each with half the number of chromosomes as the parent cell Meiosis: type of division in which four cells are formed, each with half the number of chromosomes as the parent cell

4. Terms to Know Body cells (diploid, 2n) Body cells (diploid, 2n) contain two of each kind of chromosome. contain two of each kind of chromosome. chromosomes are paired, one set from each parent chromosomes are paired, one set from each parent Paired chromosomes are called homologous chromosomes Paired chromosomes are called homologous chromosomes Human body cell: 46 chromosomes/23 pairs Human body cell: 46 chromosomes/23 pairs

5. Terms to Know Gamete (haploid, n) Gamete (haploid, n) Also called a “sex cell” Also called a “sex cell” Contains one of each kind of chromosome (or half the number of a body cells) Contains one of each kind of chromosome (or half the number of a body cells) Human sex cell (sperm or egg): 23 chromosomes Human sex cell (sperm or egg): 23 chromosomes Zygote Zygote the result of the fertilization of an egg cell with a sperm cell forming a diploid cell the result of the fertilization of an egg cell with a sperm cell forming a diploid cell

6. Meiosis fertilization is the process in which two haploid cells come together to form a unique diploid fertilization is the process in which two haploid cells come together to form a unique diploid This is the premise of sexual reproduction This is the premise of sexual reproduction

7. Meiosis Interphase: stage in which chromosomes duplicate themselves (same as mitosis) Interphase: stage in which chromosomes duplicate themselves (same as mitosis) Meiosis is then separated into two division stages Meiosis is then separated into two division stages Meiosis I and Meiosis II Meiosis I and Meiosis II

8. Phases of Meiosis http://player.discoveryeducation.com/index.cf m?guidAssetId=9965DAF6-2344-4A14-8A87- 085F0139FB50&blnFromSearch=1&productco de=US http://player.discoveryeducation.com/index.cf m?guidAssetId=9965DAF6-2344-4A14-8A87- 085F0139FB50&blnFromSearch=1&productco de=US http://player.discoveryeducation.com/index.cf m?guidAssetId=9965DAF6-2344-4A14-8A87- 085F0139FB50&blnFromSearch=1&productco de=US http://player.discoveryeducation.com/index.cf m?guidAssetId=9965DAF6-2344-4A14-8A87- 085F0139FB50&blnFromSearch=1&productco de=US

9. Meiosis I Prophase I Prophase I Chromosomes coil and spindle forms Chromosomes coil and spindle forms Each pair of homologous chromosomes and their sister chromatids come together to form a four-part tetrad joined together by a centromere Each pair of homologous chromosomes and their sister chromatids come together to form a four-part tetrad joined together by a centromere

10. Meiosis I Prophase I Prophase I During this phase, an exchange of genetic material may occur between two non-sister chromatids (crossing over) During this phase, an exchange of genetic material may occur between two non-sister chromatids (crossing over) Crossing over allows for more variation in sexual reproduction Crossing over allows for more variation in sexual reproduction

11. Meiosis I Metaphase I Metaphase I Chromosomes become attached to spindle Chromosomes become attached to spindle Tetrads are pulled to the mid-line of the cell Tetrads are pulled to the mid-line of the cell

12. Meiosis I Anaphase I Anaphase I Homologous chromosomes, along with their sister chromatids, separate Homologous chromosomes, along with their sister chromatids, separate

13. Meiosis I Telophase I Telophase I Spindle breaks down Spindle breaks down Chromosomes uncoil Chromosomes uncoil Cytoplasm divides to form two new cells Cytoplasm divides to form two new cells * Each cell has half the genetic information as the original parent cell, BUT the chromosomes are still doubled so another division must take place

14. Meiosis II Prophase II Prophase II A spindle forms and the chromosomes in each cell attach A spindle forms and the chromosomes in each cell attach Sister chromatids are pulled to the center of the cell Sister chromatids are pulled to the center of the cell

15. Meiosis II Metaphase II Metaphase II Sister chromatids line up on the mid-line of the cells Sister chromatids line up on the mid-line of the cells

16. Meiosis II Anaphase II Anaphase II The centromere breaks allowing the sister chromatids to migrate to opposite ends the cells The centromere breaks allowing the sister chromatids to migrate to opposite ends the cells

17. Meiosis II Telophase II Telophase II Nuclei reform Nuclei reform Spindles break down Spindles break down Cytoplasm splits Cytoplasm splits

18. End of Meiosis Meiosis produces FOUR haploid cells, each containing one chromosome from each homologous pair

19. Meiosis genetic recombination: the reassortment of chromosomes and the genetic information they carry, providing a major source of genetic variation

20. How much variation? “n”: The number of homologous pairs in a cell “n”: The number of homologous pairs in a cell Human body cell contains 46 chromosomes (23 homologous pairs) Human body cell contains 46 chromosomes (23 homologous pairs) 2n=46 2n=46 Human sperm cell contains 23 chromosomes (one representative from each homologous pair) n=23 Human sperm cell contains 23 chromosomes (one representative from each homologous pair) n=23 Human egg cell (same as sperm) Human egg cell (same as sperm) n=23 n=23

21. WOW!!! Possible different kinds of egg or sperm cells created by a person = 2²³ or 8.4 million Possible different kinds of egg or sperm cells created by a person = 2²³ or 8.4 million Fertilization of one egg by one sperm results in Fertilization of one egg by one sperm results in 2²³ x 2²³ or 70 trillion possible zygote combinations 2²³ x 2²³ or 70 trillion possible zygote combinations * This does not take into consideration possible crossovers that occur during prophase I

22. End Result---We are ALL truly unique