1. Addressing a Range of Transmission Intensity 10 10.10.01 0.0010 Transmission Intensity (measured as EIR) Infections/ 1000/year 10,000100010010 1 0 Parasite Prevalence 2-9yr olds 30-60%10-30%1-10%<2% <0.3% 0 Health Facility* cases/week 150-30020-405-151-5 <1 0 * Health facility is assumed to serve ~5000 population and may include community health workers; numbers indicate confirmed malaria cases and include the notion that as infection rates are lower, an increasing proportion of infections become symptomatic. High MediumLow Very Low End GameZero

2. Steps to Accelerate to Elimination: Steps A-to-E Parasite Prevalence 30-60%10-30%1-10%<2%<0.3%0 Health Facility* cases/week 150-30020-405-151-5<10 Range of Transmission Intensity ELIMINATE DOCUMENT and MAINTAIN ZERO

3. Steps to Accelerate to Elimination: Steps A-to-E Parasite Prevalence 30-60%10-30%1-10%<2%<0.3%0 Health Facility* cases/week 150-30020-405-151-5<10 Range of Transmission Intensity ELIMINATE DOCUMENT and MAINTAIN ZERO ACCELERATE SCALE UP for Impact OPTIMIZE PREVENTION and CASE MANAGEMENT

4. Steps to Accelerate to Elimination: Steps A-to-E Parasite Prevalence 30-60%10-30%1-10%<2%<0.3%0 Health Facility* cases/week 150-30020-405-151-5<10 Range of Transmission Intensity ELIMINATE DOCUMENT and MAINTAIN ZERO ACCELERATE SCALE UP for Impact OPTIMIZE PREVENTION and CASE MANAGEMENT BUILD INFORMATION Systems for Action QUALITY and TIMELY REPORTING of INFECTIONS

5. Steps to Accelerate to Elimination: Steps A-to-E Parasite Prevalence 30-60%10-30%1-10%<2%<0.3%0 Health Facility* cases/week 150-30020-405-151-5<10 Range of Transmission Intensity ELIMINATE DOCUMENT and MAINTAIN ZERO ACCELERATE SCALE UP for Impact OPTIMIZE PREVENTION and CASE MANAGEMENT BUILD INFORMATION Systems for Action QUALITY and TIMELY REPORTING of INFECTIONS COMMUNITY CLEARANCE of Malaria Parasites POPULATION-WIDE STRATEGIES to REDUCE TRANSMISSION

6. Steps to Accelerate to Elimination: Steps A-to-E Parasite Prevalence 30-60%10-30%1-10%<2%<0.3%0 Health Facility* cases/week 150-30020-405-151-5<10 Range of Transmission Intensity ELIMINATE DOCUMENT and MAINTAIN ZERO ACCELERATE SCALE UP for Impact OPTIMIZE PREVENTION and CASE MANAGEMENT BUILD INFORMATION Systems for Action QUALITY and TIMELY REPORTING of INFECTIONS COMMUNITY CLEARANCE of Malaria Parasites POPULATION-WIDE STRATEGIES to REDUCE TRANSMISSION DETECT & INVESTIGATE Individual Cases HOUSEHOLD and NEIGHBORHOOD STRATEGIES to STOP TRANSMISSION

7. Steps to Accelerate to Elimination: Steps A-to-E Parasite Prevalence 30-60%10-30%1-10%<2%<0.3%0 Health Facility* cases/week 150-30020-405-151-5<10 Range of Transmission Intensity ELIMINATE DOCUMENT and MAINTAIN ZERO ACCELERATE SCALE UP for Impact OPTIMIZE PREVENTION and CASE MANAGEMENT BUILD INFORMATION Systems for Action QUALITY and TIMELY REPORTING of INFECTIONS COMMUNITY CLEARANCE of Malaria Parasites POPULATION-WIDE STRATEGIES to REDUCE TRANSMISSION DETECT & INVESTIGATE Individual Cases HOUSEHOLD and NEIGHBORHOOD STRATEGIES to STOP TRANSMISSION

8. Steps to Accelerate to Elimination: Steps A-to-E Parasite Prevalence 30-60%10-30%1-10%<2%<0.3%0 Health Facility* cases/week 150-30020-405-151-5<10 Range of Transmission Intensity ELIMINATE DOCUMENT and MAINTAIN ZERO DETECT & INVESTIGATE Individual Cases HOUSEHOLD and NEIGHBORHOOD STRATEGIES to STOP TRANSMISSION COMMUNITY CLEARANCE of Malaria Parasites POPULATION-WIDE STRATEGIES to REDUCE TRANSMISSION BUILD INFORMATION Systems for Action QUALITY and TIMELY REPORTING of INFECTIONS ACCELERATE SCALE UP for Impact OPTIMIZE PREVENTION and CASE MANAGEMENT