1. Chapter 42: Internal Transport

2. Fig. 42-3 Heart Hemolymph in sinuses surrounding organs Heart Interstitial fluid Small branch vessels In each organ Blood Dorsal vessel (main heart) Auxiliary heartsVentral vessels (b) A closed circulatory system (a) An open circulatory system Tubular heart Pores

3. Fig. 42-4 Artery Ventricle Atrium Heart Vein Systemic capillaries Systemic circulation Gill circulation Gill capillaries

4. Fig. 42-5 Amphibians Lung and skin capillaries Pulmocutaneous circuit Atrium (A) Ventricle (V) Atrium (A) Systemic circuit Right Left Systemic capillaries Reptiles (Except Birds) Lung capillaries Pulmonary circuit Right systemic aorta Right Left systemic aorta Systemic capillaries AA V V Pulmonary circuit Systemic circuit RightLeft AA V V Lung capillaries Mammals and Birds

5. Fig. 42-6 Superior vena cava Pulmonary artery Capillaries of right lung 3 7 3 8 9 2 4 11 5 1 10 Aorta Pulmonary vein Right atrium Right ventricle Inferior vena cava Capillaries of abdominal organs and hind limbs Pulmonary vein Left atrium Left ventricle Aorta Capillaries of left lung Pulmonary artery Capillaries of head and forelimbs

6. Fig. 42-7 Pulmonary artery Right atrium Semilunar valve Atrioventricular valve Right ventricle Left ventricle Atrioventricular valve Left atrium Semilunar valve Pulmonary artery Aorta

7. Fig. 42-8 Semilunar valves closed 0.4 sec AV valves open Atrial and ventricular diastole 1 2 0.1 sec Atrial systole; ventricular diastole 3 0.3 sec Semilunar valves open AV valves closed Ventricular systole; atrial diastole

8. Fig. 42-9-5 Signals spread throughout ventricles. 4 Purkinje fibers Pacemaker generates wave of signals to contract. 1 SA node (pacemaker) ECG Signals are delayed at AV node. 2 AV node Signals pass to heart apex. 3 Bundle branches Heart apex

9. Fig. 42-10 ArteryVein SEM 100 µm Endothelium Artery Smooth muscle Connective tissue Capillary Basal lamina Endothelium Smooth muscle Connective tissue Valve Vein Arteriole Venule Red blood cell Capillary 15 µm LM

10. Fig. 42-17 Plasma 55% ConstituentMajor functions Water Solvent for carrying other substances Ions (blood electrolytes) Osmotic balance, pH buffering, and regulation of membrane permeability Sodium Potassium Calcium Magnesium Chloride Bicarbonate Osmotic balance pH buffering Clotting Defense Plasma proteins Albumin Fibrinogen Immunoglobulins (antibodies) Substances transported by blood Nutrients (such as glucose, fatty acids, vitamins) Waste products of metabolism Respiratory gases (O 2 and CO 2 ) Hormones Separated blood elements Cellular elements 45% Cell typeFunctionsNumber per µL (mm 3 ) of blood Erythrocytes (red blood cells) 5–6 million Transport oxygen and help transport carbon dioxide Leukocytes (white blood cells) 5,000–10,000 Defense and immunity Basophil Neutrophil Eosinophil Lymphocyte Monocyte PlateletsBlood clotting 250,000– 400,000

11. Collagen fibers Platelet plug Platelet releases chemicals that make nearby platelets sticky Clotting factors from: Platelets Damaged cells Plasma (factors include calcium, vitamin K) ProthrombinThrombin FibrinogenFibrin 5 µm Fibrin clot Red blood cell Fig. 42-18-4