1. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 ACI GRID 2002 MEDIGRID: high performance medical image processing on a computational grid (accepted 3 years project) CREATIS (INSA Lyon) J. Montagnat LISI (INSA Lyon) L. Brunie ERIC (University Lyon 2) S. Miguet

2. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Purposes u Medical image storage and processing on the grid n Structured data n Strong semantic (distributed medical files) n Sensitive (security issues) u Process complex algorithms with large computing power and memory requirements n parallel processing u Handle very large data sets n distributed storage n massive distributed processing u Context: datagrid testbed.

3. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Scientific challenges u Shared and distributed data management n data hierarchy, dynamic indices, optimization, caching u Hybrid content-based and metadata queries n content-based queries, pre-processing, distributed queries u Complex modeling of anatomical structures n anatomical and functional models, parallelisation u Simulation of MRIs n MRI modeling, artifacts modeling, parallel simulation

4. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Data and users u Medical Data n Images and metadata n Nominative (critical) and non-nominative (private) data n DICOM3 for medical images u Users n Patient: has free access to its medical data. n Physician: has complete read access to its patients data. Few persons have read/write access. n Researchers: may obtain read access to anonymous medical data for research purposes. Nominative data should be blanked before transmission to these users.

5. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Data management requirements u Medical data requirements n Very large databases (Tb/year/hospital) and very long term storage (20 years for all images, up to 70 years in some cases) n Large amount of metadata n Access right on a medical department basis n Log data processing u Security related requirements n Data access security (Read-only access for most users, access right on a medical department basis, no read access to private data by any third party including system administrators) n Explicit control of sites where private data may be replicated n Nominative metadata should be stored in secure databases n Images should not be replicated outside hospital without blanking headers n Images content should be encrypted

6. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Data infrastructure testbed u 4 image sources: n Acquired from Lyon cardiological hospital n Bone structure database from ESRF Grenoble n Mammographies from the DDSM n Simulated images DLT Heart MRI Cardiological hospital INSABone Simulated MRI University Lyon 2 Breast images EDG Local cluster

7. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Foreseen medical data infrastructure u Split nominative and anonymous data to allow data replication on unsecured sites. Untrusted data servers with blanked images jE Authentication and Authorization Metadata interface SE-DICOM interface Confidential data Non-confidential data Header blanking hospital SE DICOM Server SE European DataGrid

8. qmsg/shm LAN WAN SE Interface jE/SE Interface hdS jE User Interface jE Dicon Client jE Dicon Server spitfire security (GSI) jE Cache hdS OK phase 1 phase 2 jE Spitfire Int ATF April 8, 2002, H. Duque, WP10 Interaction with DataGrid middleware

9. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Applications u Image database importation n Pre-processing of images for database indexing n Data distribution u Hybrid content-based and metadata queries n Triggering parallel processing, distributed queries, DICOM server interface n pipeline processing u MRI simulation n parallel simulation kernel u Heart segmentation from MRI sequences n heart modeling, parallel job execution

10. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Application example: Metadata query and image processing

11. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Schedule u year 1 n setting up databases n statistical parameters computation n image indexing n spitfire-based security n MRI simulator n grid interface to DICOM servers u year 2 n interface with datagrid / remote processing n distributed data management n spitfire extensions n content-based and metadata queries pipeline processing

12. MEDIGRID project, DataGrid FR meeting, April 18, 2002, Johan Montagnat, WP10 Schedule u year 3 n distributed data management n biomedical modeling n mammography studies n cardiac studies n first medical assessment