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Kaitlyn McConville, Rho ®, Inc. Kristen Much, Rho ®, Inc. PharmaSUG 2015 Paper #DV02.

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Presentation on theme: "Kaitlyn McConville, Rho ®, Inc. Kristen Much, Rho ®, Inc. PharmaSUG 2015 Paper #DV02."— Presentation transcript:

1 Kaitlyn McConville, Rho ®, Inc. Kristen Much, Rho ®, Inc. PharmaSUG 2015 Paper #DV02

2 2  Step 1 GTL Overview  Step 2

3 3  TMPLOUT Shortcut!

4 GTL_Code.sas 4

5 5 Scatter Plot Overlaid on Box Plot Example 1 5

6 6

7 The Motivation 7

8 The Code proc template; define statgraph scatterbox; begingraph; entrytitle "Area Under the Curve (pmol/mL) over Time by Treatment Group"; layout overlay / xaxisopts=( ) yaxisopts=( ); drawtext textattrs=(size=8pt) "Treatment Difference: &treat_auc." / ; drawtext textattrs=(size=8pt) "Time Trend: &time_auc." / ; drawtext textattrs=(size=8pt) "Treatment by Time: &trtbtime_auc." / ; drawtext textattrs=(size=8pt) "N = &n0_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p0_auc." / ; drawtext textattrs=(size=8pt) "N = &n6_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p6_auc." / ;; drawtext textattrs=(size=8pt) "N = &n12_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p12_auc." / ; drawtext textattrs=(size=8pt) "N = &n18_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p18_auc." / ; drawtext textattrs=(size=8pt) "N = &n24_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p24_auc." / ; scatterplot x=eval(0.4*rannor(57)+visitn2) y=auc / group=trt name="trt1" ; boxplot x=visitn2 y=auc / group=trt display=(caps mean median connect) connect=mean name="trt2"; mergedlegend "trt1" "trt2" / title="Treatment"; endlayout; endgraph; end; run; proc sgrender data=datasetname template=scatterbox; run; 8

9 The Code proc template; define statgraph scatterbox; begingraph; entrytitle "Area Under the Curve (pmol/mL) over Time by Treatment Group"; layout overlay / xaxisopts=( ) yaxisopts=( ); drawtext textattrs=(size=8pt) "Treatment Difference: &treat_auc." / ; drawtext textattrs=(size=8pt) "Time Trend: &time_auc." / ; drawtext textattrs=(size=8pt) "Treatment by Time: &trtbtime_auc." / ; drawtext textattrs=(size=8pt) "N = &n0_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p0_auc." / ; drawtext textattrs=(size=8pt) "N = &n6_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p6_auc." / ;; drawtext textattrs=(size=8pt) "N = &n12_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p12_auc." / ; drawtext textattrs=(size=8pt) "N = &n18_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p18_auc." / ; drawtext textattrs=(size=8pt) "N = &n24_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p24_auc." / ; scatterplot x=eval(0.4*rannor(57)+visitn2) y=auc / group=trt name="trt1" ; boxplot x=visitn2 y=auc / group=trt display=(caps mean median connect) connect=mean name="trt2"; mergedlegend "trt1" "trt2" / title="Treatment"; endlayout; endgraph; end; run; proc sgrender data=datasetname template=scatterbox; run; 9

10 The Code proc template; define statgraph scatterbox; begingraph; entrytitle "Area Under the Curve (pmol/mL) over Time by Treatment Group"; layout overlay / xaxisopts=( ) yaxisopts=( ); drawtext textattrs=(size=8pt) "Treatment Difference: &treat_auc." / ; drawtext textattrs=(size=8pt) "Time Trend: &time_auc." / ; drawtext textattrs=(size=8pt) "Treatment by Time: &trtbtime_auc." / ; drawtext textattrs=(size=8pt) "N = &n0_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p0_auc." / ; drawtext textattrs=(size=8pt) "N = &n6_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p6_auc." / ;; drawtext textattrs=(size=8pt) "N = &n12_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p12_auc." / ; drawtext textattrs=(size=8pt) "N = &n18_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p18_auc." / ; drawtext textattrs=(size=8pt) "N = &n24_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p24_auc." / ; scatterplot x=eval(0.4*rannor(57)+visitn2) y=auc / group=trt name="trt1" ; boxplot x=visitn2 y=auc / group=trt display=(caps mean median connect) connect=mean name="trt2"; mergedlegend "trt1" "trt2" / title="Treatment"; endlayout; endgraph; end; run; proc sgrender data=datasetname template=scatterbox; run; 10

11 11

12 The Code proc template; define statgraph scatterbox; begingraph; entrytitle "Area Under the Curve (pmol/mL) over Time by Treatment Group"; layout overlay / xaxisopts=( ) yaxisopts=( ); drawtext textattrs=(size=8pt) "Treatment Difference: &treat_auc." / ; drawtext textattrs=(size=8pt) "Time Trend: &time_auc." / ; drawtext textattrs=(size=8pt) "Treatment by Time: &trtbtime_auc." / ; drawtext textattrs=(size=8pt) "N = &n0_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p0_auc." / ; drawtext textattrs=(size=8pt) "N = &n6_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p6_auc." / ;; drawtext textattrs=(size=8pt) "N = &n12_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p12_auc." / ; drawtext textattrs=(size=8pt) "N = &n18_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p18_auc." / ; drawtext textattrs=(size=8pt) "N = &n24_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p24_auc." / ; scatterplot x=eval(0.4*rannor(57)+visitn2) y=auc / group=trt name="trt1" ; boxplot x=visitn2 y=auc / group=trt display=(caps mean median connect) connect=mean name="trt2"; mergedlegend "trt1" "trt2" / title="Treatment"; endlayout; endgraph; end; run; proc sgrender data=datasetname template=scatterbox; run; 12

13 13

14 The Code proc template; define statgraph scatterbox; begingraph; entrytitle "Area Under the Curve (pmol/mL) over Time by Treatment Group"; layout overlay / xaxisopts=( ) yaxisopts=( ); drawtext textattrs=(size=8pt) "Treatment Difference: &treat_auc." / ; drawtext textattrs=(size=8pt) "Time Trend: &time_auc." / ; drawtext textattrs=(size=8pt) "Treatment by Time: &trtbtime_auc." / ; drawtext textattrs=(size=8pt) "N = &n0_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p0_auc." / ; drawtext textattrs=(size=8pt) "N = &n6_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p6_auc." / ;; drawtext textattrs=(size=8pt) "N = &n12_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p12_auc." / ; drawtext textattrs=(size=8pt) "N = &n18_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p18_auc." / ; drawtext textattrs=(size=8pt) "N = &n24_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p24_auc." / ; scatterplot x=eval(0.4*rannor(57)+visitn2) y=auc / group=trt name="trt1" ; boxplot x=visitn2 y=auc / group=trt display=(caps mean median connect) connect=mean name="trt2"; mergedlegend "trt1" "trt2" / title="Treatment"; endlayout; endgraph; end; run; proc sgrender data=datasetname template=scatterbox; run; 14

15 15

16 The Code proc template; define statgraph scatterbox; begingraph; entrytitle "Area Under the Curve (pmol/mL) over Time by Treatment Group"; layout overlay / xaxisopts=( ) yaxisopts=( ); drawtext textattrs=(size=8pt) "Treatment Difference: &treat_auc." / ; drawtext textattrs=(size=8pt) "Time Trend: &time_auc." / ; drawtext textattrs=(size=8pt) "Treatment by Time: &trtbtime_auc." / ; drawtext textattrs=(size=8pt) "N = &n0_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p0_auc." / ; drawtext textattrs=(size=8pt) "N = &n6_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p6_auc." / ;; drawtext textattrs=(size=8pt) "N = &n12_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p12_auc." / ; drawtext textattrs=(size=8pt) "N = &n18_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p18_auc." / ; drawtext textattrs=(size=8pt) "N = &n24_auc." / ; drawtext textattrs=(size=8pt) "p-value = &p24_auc." / ; scatterplot x=eval(0.4*rannor(57)+visitn2) y=auc / group=trt name="trt1" ; boxplot x=visitn2 y=auc / group=trt display=(caps mean median connect) connect=mean name="trt2"; mergedlegend "trt1" "trt2" / title="Treatment"; endlayout; endgraph; end; run; proc sgrender data=datasetname template=scatterbox; run; 16

17 17

18 18 Multi-cell Graph with Nested Layout Lattice Example 2 18

19 19

20 The Code proc template; define statgraph mri; begingraph; entrytitle 'Baseline MRI Characteristics'; layout lattice /rows=1 columns=2 columnweights=(0.6 0.4) columngutter=.5cm; layout overlay / yaxisopts=(griddisplay=on); histogram t2vol / binaxis=false; densityplot t2vol / lineattrs=graphfit name='density' legendlabel=’Normal’; discretelegend 'density' / location=inside halign=left valign=top; layout gridded / rows=5 columns=2 opaque=true border=true autoalign=(topright); entry halign=left 'Mean'; entry halign=right "&mean"; entry halign=left 'Std.Dev'; entry halign=right "&std"; entry halign=left 'Median'; entry halign=right "&med"; entry halign=left 'Min'; entry halign=right "&min"; entry halign=left 'Max'; entry halign=right "&max"; endlayout; layout lattice / rows=2 columns=1 rowgutter=.5cm; layout overlay / yaxisopts=(griddisplay=on linearopts=(tickvaluelist=(0 3 6 9 12 15))); barchart x=gadc; endlayout; layout overlay / xaxisopts=(linearopts=(viewmax=4)); scatterplot x=t1vol y=t2vol; endlayout; endgraph; end; run; proc sgrender data=datasetname template=mri; run; 20

21 The Code proc template; define statgraph mri; begingraph; entrytitle 'Baseline MRI Characteristics'; layout lattice /rows=1 columns=2 columnweights=(0.6 0.4) columngutter=.5cm; layout overlay / yaxisopts=(griddisplay=on); histogram t2vol / binaxis=false; densityplot t2vol / lineattrs=graphfit name='density' legendlabel=’Normal’; discretelegend 'density' / location=inside halign=left valign=top; layout gridded / rows=5 columns=2 opaque=true border=true autoalign=(topright); entry halign=left 'Mean'; entry halign=right "&mean"; entry halign=left 'Std.Dev'; entry halign=right "&std"; entry halign=left 'Median'; entry halign=right "&med"; entry halign=left 'Min'; entry halign=right "&min"; entry halign=left 'Max'; entry halign=right "&max"; endlayout; layout lattice / rows=2 columns=1 rowgutter=.5cm; layout overlay / yaxisopts=(griddisplay=on linearopts=(tickvaluelist=(0 3 6 9 12 15))); barchart x=gadc; endlayout; layout overlay / xaxisopts=(linearopts=(viewmax=4)); scatterplot x=t1vol y=t2vol; endlayout; endgraph; end; run; proc sgrender data=datasetname template=mri; run; 21

22 The Code proc template; define statgraph mri; begingraph; entrytitle 'Baseline MRI Characteristics'; layout lattice /rows=1 columns=2 columnweights=(0.6 0.4) columngutter=.5cm; layout overlay / yaxisopts=(griddisplay=on); histogram t2vol / binaxis=false; densityplot t2vol / lineattrs=graphfit name='density' legendlabel=’Normal’; discretelegend 'density' / location=inside halign=left valign=top; layout gridded / rows=5 columns=2 opaque=true border=true autoalign=(topright); entry halign=left 'Mean'; entry halign=right "&mean"; entry halign=left 'Std.Dev'; entry halign=right "&std"; entry halign=left 'Median'; entry halign=right "&med"; entry halign=left 'Min'; entry halign=right "&min"; entry halign=left 'Max'; entry halign=right "&max"; endlayout; layout lattice / rows=2 columns=1 rowgutter=.5cm; layout overlay / yaxisopts=(griddisplay=on linearopts=(tickvaluelist=(0 3 6 9 12 15))); barchart x=gadc; endlayout; layout overlay / xaxisopts=(linearopts=(viewmax=4)); scatterplot x=t1vol y=t2vol; endlayout; endgraph; end; run; proc sgrender data=datasetname template=mri; run; 22

23 23

24 The Code proc template; define statgraph mri; begingraph; entrytitle 'Baseline MRI Characteristics'; layout lattice /rows=1 columns=2 columnweights=(0.6 0.4) columngutter=.5cm; layout overlay / yaxisopts=(griddisplay=on); histogram t2vol / binaxis=false; densityplot t2vol / lineattrs=graphfit name='density' legendlabel=’Normal’; discretelegend 'density' / location=inside halign=left valign=top; layout gridded / rows=5 columns=2 opaque=true border=true autoalign=(topright); entry halign=left 'Mean'; entry halign=right "&mean"; entry halign=left 'Std.Dev'; entry halign=right "&std"; entry halign=left 'Median'; entry halign=right "&med"; entry halign=left 'Min'; entry halign=right "&min"; entry halign=left 'Max'; entry halign=right "&max"; endlayout; layout lattice / rows=2 columns=1 rowgutter=.5cm; layout overlay / yaxisopts=(griddisplay=on linearopts=(tickvaluelist=(0 3 6 9 12 15))); barchart x=gadc; endlayout; layout overlay / xaxisopts=(linearopts=(viewmax=4)); scatterplot x=t1vol y=t2vol; endlayout; endgraph; end; run; proc sgrender data=datasetname template=mri; run; 24

25 25

26 The Code proc template; define statgraph mri; begingraph; entrytitle 'Baseline MRI Characteristics'; layout lattice /rows=1 columns=2 columnweights=(0.6 0.4) columngutter=.5cm; layout overlay / yaxisopts=(griddisplay=on); histogram t2vol / binaxis=false; densityplot t2vol / lineattrs=graphfit name='density' legendlabel=’Normal’; discretelegend 'density' / location=inside halign=left valign=top; layout gridded / rows=5 columns=2 opaque=true border=true autoalign=(topright); entry halign=left 'Mean'; entry halign=right "&mean"; entry halign=left 'Std.Dev'; entry halign=right "&std"; entry halign=left 'Median'; entry halign=right "&med"; entry halign=left 'Min'; entry halign=right "&min"; entry halign=left 'Max'; entry halign=right "&max"; endlayout; layout lattice / rows=2 columns=1 rowgutter=.5cm; layout overlay / yaxisopts=(griddisplay=on linearopts=(tickvaluelist=(0 3 6 9 12 15))); barchart x=gadc; endlayout; layout overlay / xaxisopts=(linearopts=(viewmax=4)); scatterplot x=t1vol y=t2vol; endlayout; endgraph; end; run; proc sgrender data=datasetname template=mri; run; 26

27 The Code proc template; define statgraph mri; begingraph; entrytitle 'Baseline MRI Characteristics'; layout lattice /rows=1 columns=2 columnweights=(0.6 0.4) columngutter=.5cm; layout overlay / yaxisopts=(griddisplay=on); histogram t2vol / binaxis=false; densityplot t2vol / lineattrs=graphfit name='density' legendlabel=’Normal’; discretelegend 'density' / location=inside halign=left valign=top; layout gridded / rows=5 columns=2 opaque=true border=true autoalign=(topright); entry halign=left 'Mean'; entry halign=right "&mean"; entry halign=left 'Std.Dev'; entry halign=right "&std"; entry halign=left 'Median'; entry halign=right "&med"; entry halign=left 'Min'; entry halign=right "&min"; entry halign=left 'Max'; entry halign=right "&max"; endlayout; layout lattice / rows=2 columns=1 rowgutter=.5cm; layout overlay / yaxisopts=(griddisplay=on linearopts=(tickvaluelist=(0 3 6 9 12 15))); barchart x=gadc; endlayout; layout overlay / xaxisopts=(linearopts=(viewmax=4)); scatterplot x=t1vol y=t2vol; endlayout; endgraph; end; run; proc sgrender data=datasetname template=mri; run; 27

28 28

29 The Code proc template; define statgraph mri; begingraph; entrytitle 'Baseline MRI Characteristics'; layout lattice /rows=1 columns=2 columnweights=(0.6 0.4) columngutter=.5cm; layout overlay / yaxisopts=(griddisplay=on); histogram t2vol / binaxis=false; densityplot t2vol / lineattrs=graphfit name='density' legendlabel=’Normal’; discretelegend 'density' / location=inside halign=left valign=top; layout gridded / rows=5 columns=2 opaque=true border=true autoalign=(topright); entry halign=left 'Mean'; entry halign=right "&mean"; entry halign=left 'Std.Dev'; entry halign=right "&std"; entry halign=left 'Median'; entry halign=right "&med"; entry halign=left 'Min'; entry halign=right "&min"; entry halign=left 'Max'; entry halign=right "&max"; endlayout; layout lattice / rows=2 columns=1 rowgutter=.5cm; layout overlay / yaxisopts=(griddisplay=on linearopts=(tickvaluelist=(0 3 6 9 12 15))); barchart x=gadc; endlayout; layout overlay / xaxisopts=(linearopts=(viewmax=4)); scatterplot x=t1vol y=t2vol; endlayout; endgraph; end; run; proc sgrender data=datasetname template=mri; run; 29

30 The Code proc template; define statgraph mri; begingraph; entrytitle 'Baseline MRI Characteristics'; layout lattice /rows=1 columns=2 columnweights=(0.6 0.4) columngutter=.5cm; layout overlay / yaxisopts=(griddisplay=on); histogram t2vol / binaxis=false; densityplot t2vol / lineattrs=graphfit name='density' legendlabel=’Normal’; discretelegend 'density' / location=inside halign=left valign=top; layout gridded / rows=5 columns=2 opaque=true border=true autoalign=(topright); entry halign=left 'Mean'; entry halign=right "&mean"; entry halign=left 'Std.Dev'; entry halign=right "&std"; entry halign=left 'Median'; entry halign=right "&med"; entry halign=left 'Min'; entry halign=right "&min"; entry halign=left 'Max'; entry halign=right "&max"; endlayout; layout lattice / rows=2 columns=1 rowgutter=.5cm; layout overlay / yaxisopts=(griddisplay=on linearopts=(tickvaluelist=(0 3 6 9 12 15))); barchart x=gadc; endlayout; layout overlay / xaxisopts=(linearopts=(viewmax=4)); scatterplot x=t1vol y=t2vol; endlayout; endgraph; end; run; proc sgrender data=datasetname template=mri; run; 30

31 31

32 32 Multi-cell Paneled Series Plots Example 3 32

33 33

34 The Code proc template; define statgraph twobyone; begingraph / designwidth=11in designheight=8.5in; layout gridded / rows=2 columns=1 rowgutter=15; drawtext textattrs=(size=30pt) "A" / ; drawtext textattrs=(size=30pt) "B" / ; layout datapanel classvars=(id) / ; layout prototype; seriesplot x=visit0 y=cpep / legendlabel="Baseline Visit" name="y0“ lineattrs=( ); seriesplot x=visit6 y=cpep / legendlabel="Month 6 Visit" name="y1" lineattrs=( ); seriesplot x=visit12 y=cpep / legendlabel="Month 12 Visit" name="y2" lineattrs=( ); seriesplot x=visit18 y=cpep / legendlabel="Month 18 Visit" name="y3" lineattrs=( ); seriesplot x=visit24 y=cpep / legendlabel="Month 24 Visit" name="y4" lineattrs=( ); endlayout; layout datapanel classvars=(id) / ; layout prototype; seriesplot x=visit0 y=glucose / lineattrs=( ); seriesplot x=visit6 y=glucose / lineattrs=( ); seriesplot x=visit22 y=glucose / lineattrs=( ); seriesplot x=visit18 y=glucose / lineattrs=( ); seriesplot x=visit24 y=glucose / lineattrs=( ); endlayout; discretelegend "y0" "y1" "y2" "y3" "y4" / across=5 border=true valueattrs=(size=10pt); endlayout; endgraph; end; run; proc sgrender data=datasetname template=twobyone; run; 34

35 The Code proc template; define statgraph twobyone; begingraph / designwidth=11in designheight=8.5in; layout gridded / rows=2 columns=1 rowgutter=15; drawtext textattrs=(size=30pt) "A" / ; drawtext textattrs=(size=30pt) "B" / ; layout datapanel classvars=(id) / ; layout prototype; seriesplot x=visit0 y=cpep / legendlabel="Baseline Visit" name="y0“ lineattrs=( ); seriesplot x=visit6 y=cpep / legendlabel="Month 6 Visit" name="y1" lineattrs=( ); seriesplot x=visit12 y=cpep / legendlabel="Month 12 Visit" name="y2" lineattrs=( ); seriesplot x=visit18 y=cpep / legendlabel="Month 18 Visit" name="y3" lineattrs=( ); seriesplot x=visit24 y=cpep / legendlabel="Month 24 Visit" name="y4" lineattrs=( ); endlayout; layout datapanel classvars=(id) / ; layout prototype; seriesplot x=visit0 y=glucose / lineattrs=( ); seriesplot x=visit6 y=glucose / lineattrs=( ); seriesplot x=visit22 y=glucose / lineattrs=( ); seriesplot x=visit18 y=glucose / lineattrs=( ); seriesplot x=visit24 y=glucose / lineattrs=( ); endlayout; discretelegend "y0" "y1" "y2" "y3" "y4" / across=5 border=true valueattrs=(size=10pt); endlayout; endgraph; end; run; proc sgrender data=datasetname template=twobyone; run; 35

36 36

37 The Code proc template; define statgraph twobyone; begingraph / designwidth=11in designheight=8.5in; layout gridded / rows=2 columns=1 rowgutter=15; drawtext textattrs=(size=30pt) "A" / ; drawtext textattrs=(size=30pt) "B" / ; layout datapanel classvars=(id) / ; layout prototype; seriesplot x=visit0 y=cpep / legendlabel="Baseline Visit" name="y0“ lineattrs=( ); seriesplot x=visit6 y=cpep / legendlabel="Month 6 Visit" name="y1" lineattrs=( ); seriesplot x=visit12 y=cpep / legendlabel="Month 12 Visit" name="y2" lineattrs=( ); seriesplot x=visit18 y=cpep / legendlabel="Month 18 Visit" name="y3" lineattrs=( ); seriesplot x=visit24 y=cpep / legendlabel="Month 24 Visit" name="y4" lineattrs=( ); endlayout; layout datapanel classvars=(id) / ; layout prototype; seriesplot x=visit0 y=glucose / lineattrs=( ); seriesplot x=visit6 y=glucose / lineattrs=( ); seriesplot x=visit22 y=glucose / lineattrs=( ); seriesplot x=visit18 y=glucose / lineattrs=( ); seriesplot x=visit24 y=glucose / lineattrs=( ); endlayout; discretelegend "y0" "y1" "y2" "y3" "y4" / across=5 border=true valueattrs=(size=10pt); endlayout; endgraph; end; run; proc sgrender data=datasetname template=twobyone; run; 37

38 38

39 The Code proc template; define statgraph twobyone; begingraph / designwidth=11in designheight=8.5in; layout gridded / rows=2 columns=1 rowgutter=15; drawtext textattrs=(size=30pt) "A" / ; drawtext textattrs=(size=30pt) "B" / ; layout datapanel classvars=(id) / ; layout prototype; seriesplot x=visit0 y=cpep / legendlabel="Baseline Visit" name="y0“ lineattrs=( ); seriesplot x=visit6 y=cpep / legendlabel="Month 6 Visit" name="y1" lineattrs=( ); seriesplot x=visit12 y=cpep / legendlabel="Month 12 Visit" name="y2" lineattrs=( ); seriesplot x=visit18 y=cpep / legendlabel="Month 18 Visit" name="y3" lineattrs=( ); seriesplot x=visit24 y=cpep / legendlabel="Month 24 Visit" name="y4" lineattrs=( ); endlayout; layout datapanel classvars=(id) / ; layout prototype; seriesplot x=visit0 y=glucose / lineattrs=( ); seriesplot x=visit6 y=glucose / lineattrs=( ); seriesplot x=visit22 y=glucose / lineattrs=( ); seriesplot x=visit18 y=glucose / lineattrs=( ); seriesplot x=visit24 y=glucose / lineattrs=( ); endlayout; discretelegend "y0" "y1" "y2" "y3" "y4" / across=5 border=true valueattrs=(size=10pt); endlayout; endgraph; end; run; proc sgrender data=datasetname template=twobyone; run; 39

40 40

41 Conclusion 41

42 Name: Kaitlyn McConville Enterprise: Rho, Inc. Address: 6330 Quadrangle Dr. City, State ZIP: Chapel Hill, NC 27517 Work Phone: 919-408-8000 Fax: 919-408-0999 E-mail: kaitlyn_mcconville@rhoworld.com 42 Name: Kristen Much Enterprise: Rho, Inc. Address: 6330 Quadrangle Dr. City, State ZIP: Chapel Hill, NC 27514 Work Phone: 919-408-8000 Fax: 919-408-0999 E-mail: kristen_much@rhoworld.com

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