1. Analytic Chemistry Spring, 2008 by 駱碧秀老師 醫學一 A ： 13:10-14:00 (Mon. at E307) & 8:10-10:10 (Tue. at C108) 醫學一 B ： 10:10-12:00 (Tue. at C107) & 13:10-14:00 (Wed. at E307) Office ： 醫學大樓 6F ，自然科共同實驗室，分機： 5018 教學網站： http://memo.cgu.edu.tw/bih-show/ http://memo.cgu.edu.tw/bih-show/ E-mail: blou@mail.cgu.edu.tw Office Hours: Mon. Wed.17:10-18:30

2. Lecture & Assignment Schedule: WeekDateTopics 12/25-27Introduction & Naming Compounds 23/03-05Chapter 3 Math Toolkit 33/10-12Chapter 4 Statistics 43/17-19Chapter 9~10 Buffers & Titrations 53/24-26Chapter 11 Polyprotic Acids & Bases 64/01 期中考 I (18:00) 74/07-09Chapter 18 Let There Be Light 84/14-16Chapter 19 Spectrometry 94/21-23Chapter 19 Spectrometry 104/28-4/30Chapter 14 Electrochemistry 115/05-07Chapter 15 Electrode Measurements 125/13 期中考 II (18:00) 135/19-21Chapter 13 Coordination Chemistry & EDTA Titrations 145/26-28Chapter 21 Principles of Chromatography 156/02-04Chapter 21 Principles of Chromatography 166/09-11Chapter 22 GC & LC 176/16-18 Chapter 23 Capillary Electrophoresis 1806/23 期末考 (18:00)

3. Text Book Daniel C. Harris, “ Exploring Chemical Analysis ”, 3rd Edition, 2005 by W.H. Freeman & Company.

4. Grade: 課程參與度 （含小考） : 10% 期中考 : 30% 期末考 : 30% 「成績，不只是在於你知道什麼， 而在於你表現什麼。」 成功法則第一招：一定要來上課！

5. For most its users, analytical chemistry is a tool – not an end in itself. If you are interested in biology, medicine, environmental science, geology, oceanography, or archeology, you will rely on chemical analyses to answer important questions. It is possible that you will make measurements yourself, but it is more likely that you will simply be a consumer of analytical results. What Am I Doing in This Course?

6. Goals of this course (1)To understand how analysts derive the results that you will use. (2) To understand the limitations (the uncertainties) of the results. (3) To develop laboratory skills and careful work habits that you can apply in your field.

7. This course will help you, as an informed citizen To appreciate how quantitative information is obtained and interpreted. And it should help give you a basis for positive actions in your own field of interest.

8. How do you measure the caffeine content of a chocolate bar ?

9. Extracting fat from chocolate

10. Centrifugation & Filtration

11. Chemical Analysis

12. Calibration

13. Results: FYI:

14. General Steps in a Chemical Analysis 1)Formulation the question 2)Selecting analytical procedures 3)Sampling 4)Sample preparation 5)Analysis 6)Reporting & interpretation 7)Drawing conclusions

15. Atomic elements WebElements™ periodic table http://www.webelements.com/

16. Naming Simple Compounds IUPAC - I 1. Binary compounds (Type I ; ionic) 1)cation + anion (ide) Left right 2)See p.35 rules & examples : NaCl 3)Table 2.3 sodium chlorine2.3 ide 2. Binary compounds (Type II ; ionic) –for metals with more than one type of  ion –Table 2.4 -ic / -ous2.4 –exception : IA, IIA, Al 3+, Zn 2+, Ag +

17. Naming Simple Compounds IUPAC - II 3. Polyatomic ions 1)NH 4 NO 3 NH 4 + + NO 3 - 2)Table 2.5 (memorized !!)2.5 3)O : hypo- / -ite / -ate / per- 4. Binary compounds (Type III ; covalent : nonmetals) –see p.39-40 for rules & examples –H 2 O (water), NH 3 (ammonia), CH 4 (methane) –Table 2.62.6

18. Naming chemical compounds

19. Naming acids

20. Chapter 1 Chemical Measurements Microelectrode by Optical Micrograph

21. SI units

22. Ex: Exocytosis of Neurotransmitters

24. ppm = 10 6 (mass of substance/mass of sample) ppb = 10 9 (mass of substance/mass of sample) 1ppm ～ 1ug/mL 1ppb ～ 1 ng/mL