1. 1 AIRI Statistics – Trends in NIH Awards Presented at Association of Independent Research Institutes (AIRI) 2008 Annual Meeting September 10, 2008, Washington, DC Robert F. Moore Katrina Pearson Robin M. Wagner Division of Information Services Office of Research Information Systems Office of Extramural Research/Office of the Director

2. 2 Overview Methods NIH Budget NIH Support to All Grantees - Trends NIH Support to AIRI Members - Trends Competing Applications and Success Rates Characteristics of First time and Young Investigators Summary

3. 3 Methods Data sources: PB and NIH systems Fiscal years evaluated = 1950 - 2009 Analyzed grants and contracts for current AIRI members –Exception: FY07 contracts data are excluded because they are not yet available –Evaluated budget in terms of current dollars and constant dollars adjusted for inflation –Budget figures in current dollars unless otherwise stated –Analyzed and compared data on all NIH applicants and awardees to the subset from AIRI institutions

4. 4 Fiscal Year (FY) 2009 President's Budget Request Total NIH Budget Authority $29,457 Million

5. 5 NIH Budget Authority, FYs 1983 and 2009 *BRDPI = Biomedical Research and Development Price Index Constant Dollars and Inflation BRDPI* for 1983 = 100.0

6. 6 NIH Research Grants FYs 1950 – 2007

7. 7 Yearly Change in Amount of NIH Research Grant Awards Constant Dollars, FY 1950 = 100.0

8. 8 NIH Extramural Grants by Activity, FYs 1998 and 2007 Excludes R&D Contracts

9. 9 NIH Extramural Grants by Kind of Institution, FYs 1998, 2003 and 2007 Excludes R&D Contracts

10. 10 NIH Support to AIRI Members – Percent of Total Grants ($) Excludes R&D Contracts

11. 11 NIH R&D Contracts Awarded to AIRI Members, FYs 1998 - 2006 % of NIH Budget

12. 12 Effects of Inflation on NIH Grants to AIRI Members Constant Dollars based on BRDPI FY 1998 = 100.0, FY 2007 = 138.6 Excludes R&D Contracts

13. 13 NIH Extramural Grants by Activity to AIRI Members, FYs 1998 and 2007 R&D Contracts are excluded

14. 14 NIH Grant Support to AIRI Members by Institute and Center, FY 2007 NCI $ 342,101,037NHGRI $ 41,342,255OD $ 5,469,499 NIAID $ 300,840,982NEI $ 39,107,513NIBIB $ 3,096,648 NHLBI $ 131,798,229NIMH $ 33,502,024NCCAM $ 1,777,752 NIGMS $ 117,405,635NIAMS $ 28,022,771NINR $ 804,695 NIDDK $ 78,453,017NIDA $ 26,361,771NLM $ 799,287 NINDS $ 60,069,867NIAAA $ 20,835,380FIC $ 780,436 NCRR $ 56,558,510NIDCD $ 20,775,424NCMHD $ 402,667 NIA $ 47,338,736NIDCR $ 14,431,459 NICHD $ 44,488,617NIEHS $ 10,411,092 Total NIH Grant Support to AIRI Members - $1,426,975,303 Excludes R&D Contracts

15. 15 AIRI Members Accounted for 6.7% of NIH Grant Support, FY 2007 NIAID11.4%NIA5.5%NIEHS2.6% NCI11.0%NIDDK5.4%NCCAM1.7% NHGRI9.8%NIDCR5.1%NLM1.4% NEI7.1%OD5.0%FIC1.1% NIAMS6.6%NICHD4.8%NIBIB1.1% NIDCD6.6%NCRR4.7%NINR0.7% NIGMS6.2%NINDS4.5%NCMHD0.3% NIAAA6.2%NIDA3.4% NHLBI5.6%NIMH3.0% Excludes R&D Contracts

16. 16 NIH Training and Career Awards to AIRI Members FYs 1998, 2000, 2002, 2004, 2006, and 2007

17. 17 NIH R01 Equivalent (R01, R29 AND R37) Awards, FY 2007 Average Budgeted Direct and Total Costs

18. 18 Indirect Cost (Facilities & Administration) as a Percentage of Total Cost NIH Research Grants - Excludes awards with limited facilities and administration reimbursement, and foreign and federal institutions

19. 19 NIH Competing R01 Equivalent Applications by Fiscal Year of Review

20. 20 NIH R01 Equivalent Applications by Submission Status and Award Type, FYs 1990 - 2008

21. 21 NIH Competing R01 Equivalent Applications: Amendments as % of All Applications

22. 22 Success Rates of NIH New Competing (Type 1) RO1 Equivalent Awards: Original v. Amended

23. 23 Success Rates of NIH Competing Continuation (Types 2, 4, and 9) Applications

24. 24 % of R01 Equivalent Grants Eventually Funded Based on IRG Action on Original Application

25. 25 Success Rates of Competing R01 Equivalent Applications: AIRI v. All NIH Grantees

26. 26 NIH R01 Equivalent Research Project Applications from AIRI Members

27. 27 Number of First Time R01 Equivalent Awardees: AIRI v. Other Grantees, FYs 1998 - 2007

28. 28 Average Age of Competing NIH R01 Equivalent Awardees: First time v. All, FYs 1970 – 2007

29. 29 Age of First-Time R01 Equivalent Investigators Increased since 1980, but Recently Leveled Off

30. 30 Success Rates of R01 Equivalent Applications by Type and Age of Applicant, FY 2007

31. 31 Summary - I Over the last 6 decades, the NIH budget has generally increased steadily. Since its doubling ended in 2003, the NIH budget has been about level in current dollars. However, the support provided by the NIH budget has declined in this period due to inflation. In FY 2007, AIRI members received over $1.4 billion in NIH extramural support excluding R&D contracts. AIRI members continue to receive a steady percentage of the total NIH grant budget (6.5 – 7.0 percent) A smaller percent of NIH grant support is devoted to R01 equivalents in FY 2007 (49 percent) than in FY 1998 (58 percent). The data for AIRI Institutions is similar (59.9 percent in FY 1998, 48.2 percent in FY 2007) NCI and NIAID provide the largest amount of grant support to AIRI members, both in terms of amount and percent of the Institute budget devoted to these grants.

32. 32 Summary - II Grants to AIRI cost more due to higher indirect costs. The number of distinct R01 equivalent amended applications is increasing. Amendments have higher success rates than original applications, both for competing new and continuation R01 applications. Historically, AIRI members had better success rates than the NIH average. In 2007, the gap closed and AIRI members had the about the same success rates as all NIH grantees. The trend toward older first time investigators has leveled off and remained about the same since 2000. In FY07, younger applicants had higher success rates for new R01 equivalent awards than older groups, but this pattern was not observed for competing continuations.

33. 33 Resources Award Information and Trend Data: http://report.nih.gov/award/award.cfm http://report.nih.gov/award/award.cfm Data Inquires: Dishelp@mail.nih.govDishelp@mail.nih.gov General Inquires: GrantsInfo@mail.nih.gov Application Submission: http://grants.nih.gov/grants/submitapplication.htm Contacts Robert F. Moore Consultant, Reporting Branch Division of Information Services Office of Research Information Systems Office of Extramural Research/Office of the Director National Institutes of Health 6705 Rockledge Dr., Suite 4090, Room 4174 Bethesda, MD 20892 Office: 301-435-2696 Email: moorerf@mail.nih.govmoorerf@mail.nih.gov Katrina Pearson Senior Program Analyst, Reporting Branch Division of Information Services Office of Research Information Systems Office of Extramural Research/Office of the Director National Institutes of Health 6705 Rockledge Dr., Suite 4090, Room 4168 Bethesda, MD 20892 Office: 301-435-2709 Email: pearsonk@mail.nih.govpearsonk@mail.nih.gov Robin M. Wagner Chief, Reporting Branch Division of Information Services Office of Research Information Systems Office of Extramural Research/Office of the Director National Institutes of Health 6705 Rockledge Dr., Suite 4090, Room 4188 Bethesda, MD 20892 Office: 301-443-5234 Email: wagnerr@mail.nih.govwagnerr@mail.nih.gov Contacts and Other Resources