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Cell Membranes
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Cell Membrane Views
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Phospholipid Molecule
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Hydrophilic and Hydrophobic Molecules interacting differently with water
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Wedge-shaped lipids form micelles
Cylinder-shaped lipids form bilayers
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Spontaneous sealing of phospholipid bilayer
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Liposomes
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Phospholipid mobility
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Cis-double bonds affect packing
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Cholesterol glycolipids
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Function of Cholesterol
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Phospholipid types
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Microdomains on plasma membrane
Lipid rafts Choresterol sphingolipids
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Asymmetrical distribution of phospholipids and glycolipids
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Phospholipids in cell signaling
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Phospholipase Cleavage sites
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Glycolipids
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Membrane Proteins
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Membrane Proteins
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Fatty acid chain or prenyl group modifications
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Hydropathy Plots
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B-barrel membrane proteins
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Membrane proteins are glycosylated
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A detergent micelle
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Solubilize membrane proteins with detergent
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Detergents
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Mild detergent for the solubilizing, purification, and reconstitution of membrane protein functions
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SEM image of red blood cells
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The preparation of red blood cell membranes
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15 major membrane proteins in red blood cells
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Membrane proteins are diffusable
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Proteins restrictions
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Protein distributions in a guinea pig sperm cell
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4 ways of protein restrictions
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Carbohydrate layer (Glycocalyx) on the cell surface
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Diagram of glycocalyx
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Summary Phospholipids, cholesterol, glycolipids for membrane
Asymmetric, inner and outer monolayer subcompartments and lipid functions in cell signaling membrane proteins and their anchoring models diffusion, distribution glycocalyx, proteoglycan
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Membrane Transport of Small Molecules and the Electrical Properties of Membranes
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Permeability of plasma membrane
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Carrier Protein and Channel Protein
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Transportation Models
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Electrochemical Gradient
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Ionophores
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Conformational change of a carrier protein
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Kinetics of simple and carrier-mediated diffusions
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3 ways of driving active transportation
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3 types of carrier-mediated transport
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Coupled transportation of glucose and Na+
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Transcellular transport
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Na+-K+ Pump, ATPase
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Cycles of Na+-K+ Pump
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Functions of Na+-K+ Pump
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ABC transporter 2 ATP-binding cassette domains
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A typical Ion Channel
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The gating of Ion Channels
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The Structure of bacterial K+ channel
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Gating Model of K+ channel
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Summary Membrane transportation, carrier protein, channel protein
Active transportation, passive transportation ATPases, Na+-K+ Pump Gating mechanisms of Ion Channels, K+ channel selectivity
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