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Published byHenry Knight Modified over 9 years ago
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Genetics Review Honors Human Anatomy & Physiology Mr. Mazza 2009-10
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Why review genetics in a course on anatomy & physiology? Genes control the layout, make-up and function of the bodies of all organisms. Examples of traits influenced by genes: Appearance (hair, skin, eyes, height, etc.) Body structure of an organism Susceptibility to diseases Personality traits Behavior (instincts as well as other behaviors) *Environment interacts with genes to produce the final phenotype (physical trait)
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50% of your genes from dad 50% of your genes from mom Where do your genes come from?
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It’s the stuff that genes are made of: DNA made of 4 nitrogenous bases (adenine, guanine, cytosine, thymine) A pairs with T; C pairs with G Each gene is a unique sequence of the 4 bases
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CHROMOSOME DNA gene
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What information do genes contain? Each gene on the DNA is an instruction to build a protein Proteins are the main structural components of the body (bones, muscle, skin, hair, nails, blood vessels, organs, etc.) and regulate all chemical reactions in the body
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Human Karyotype
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From Genes to Proteins
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How a protein is made DNA ribosomes mRNA (has copy of DNA information) Translation (making of a protein) Transcription (making of RNA) protein
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Each protein is made of amino acids - every 3 bases is a codon (code) for one amino acid The Genetic Code
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mutation A change in the genetic code DNARNAPROTEIN Mutated DNA Mutated RNA Defective protein Flow of genetic information in a cell (Central dogma of molecular biology):
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Why is this important? Our susceptibility to any disease is affected by the variations of genes we inherit from our parents and/or mutations we get via the environment (i.e. radiation, chemical exposure, etc.)
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