1. Virtual Biotech Model for Parkinson’s UK Arthur Roach, Director of Research

2. Conventional Biotech Strategy, Coordination, Project Mgmt Dept 1 Dept 2 Dept 3 Dept 4 Leadership Project Delivery INVESTORS £££ PROFITS £££ LICENSING PARTNERSHIPS FULL-SERVICE BIOTECH Large complex organisation with many internal functions and facilities (research, development, production, business, HR, legal, etc.) Multiple project pipeline

3. Virtual Biotech (Commercial): Essential command and control functions only Strategy, Coordination, Project Mgmt CRO 1 CRO 2 CRO 3 CRO 4 Leadership Project Delivery by External Companies INVESTORS £££ LICENSING PARTNERSHIPS VIRTUAL BIOTECH CRO = contract research organisation Essential functions only by1-10 employees Most work contracted out, including advisory board May have only one or two projects Maximum flexibility to expand, start, finish

4. Virtual Biotech Model for Parkinson’s UK Strategy, Coordination, Project Mgmt CRO 1 CRO 2 CRO 3 CRO 4 Leadership Project Delivery by External Companies Parkinson’s UK Research Budget £££ LICENSING PARTNERSHIPS Possible LLC structure with profits dedicated to support of charity ADVISORY PANEL: Industry and Scientific Expertise

5. Alternate presentation follows

6. Conventional Biotech Strategy, Coordination, Project Mgmt Dept 1 Dept 2 Dept 3 Dept 4 Leadership Project Delivery INVESTORS £££ PROFITS £££ LICENSING PARTNERSHIPS FULL-SERVICE BIOTECH

7. Virtual Biotech: Command and Control Functions Only Strategy, Coordination, Project Mgmt Dept 1 Dept 2 Dept 3 Dept 4 Leadership Project Delivery INVESTORS £££ PROFITS £££ LICENSING PARTNERSHIPS Strategy, Coordination, Project Mgmt CRO 1 CRO 2 CRO 3 CRO 4 Leadership Project Delivery by External Companies Parkinson’s UK Research Budget £££ LICENSING PARTNERSHIPS VIRTUAL BIOTECH INC.