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2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 December 2015 8:59 PM.

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Presentation on theme: "2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 December 2015 8:59 PM."— Presentation transcript:

1 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 December 2015 8:59 PM

2 Methenamine Urinary tract antiseptic Decomposes to formaldehyde in acidic environment

3 Methicillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking

4 Methimazol Antithyroid Prevents synthesis of thyroid hormones (blocks iodine organification)

5 Methotrexate Immunosuppressive Antineoplastic Folic acid antagonist Dihydrofolate reductase inhibitor

6 Methoxamine Sympathomimetic  1 adrenergic agonist Vasoconstrictor

7 Methylcellulose Bulk laxative

8 Methydopa Sympatholytic  2 adrenergic agonist Antihypertensive

9 Methylphenidate Indirect sympathomimetic Drug of abuse ADD treatment Stimulant

10 Methylprednisolone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Not by inhalation

11 Methyltestosterone Androgen Synthetic oral

12 Metipranolol Sympatholytic  adrenergic antagonist Bronchoconstrictor

13 Metoclopramide Prokinetic agent Antiemetic D 2 antagonist

14 Metocurine Paralytic Paralyzes skeletal muscles

15 Metolazone Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive

16 Metoprolol Sympatholytic  1 adrenergic antagonist Antihypertensive Heart failure medication Bronchoconstrictor

17 Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA

18 Metyrapone Glucocorticoid antagonist

19 Mexilitine Class I antiarrhythmic Na + channel blocker (activated and inactivated channels)

20 Miconazole Imidazole antifungal Inhibits synthesis of ergosterol by inhibiting lanosterol 14  demethylase

21 Midazolam Sedative hypnotic Short-acting benzodiazopine

22 Mifepristone (RU-486) Progesterone antagonist

23 Miglitol Oral hypoglycemic Alpha-glucosidase inhibitor Inhibits intestinal glucose absorption

24 Mineral oil Lubricating laxative Stool softener

25 Minocycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

26 Minoxidil Vasodilator Antihypertensive

27 Misoprostol Prostaglandin Antiulcer

28 Mitomycin C Antineoplastic Natural product Antibiotic

29 Mivacurium Paralytic Paralyzes skeletal muscles

30 Moezipril Antihypertensive Converting enzyme inhibitor

31 Montelukast Leukotriene inhibitor LTR1 and LTD4 antagonist Asthma treatment

32 Moricizine Class I antiarrhythmic Na + channel blocker

33 Morphine Opioid Analgesic  receptor agonist

34 Muromonab-CD3 Immunosuppressive Mouse monoclonal anti-CD3 antibody Organ transplant (anti-rejection)

35 Mycophenolate Immunosuppressive Inhibits inosine monophosphate dehydrogenase activity

36 Nadolol Sympatholytic  adrenergic antagonist Antihypertensive

37 Nafarelin Gonadotropin releasing hormone (GnRH) agonist

38 Nafcillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking

39 Nalbuphine Opioid antagonist  receptor antagonist

40 Nalidixic acid Urinary tract antiseptic Quinolone Inhibits bacterial DNA gyrase

41 Nalmefene Opioid antagonist

42 Nalorphine Opioid antagonist

43 Naloxone Opioid antagonist

44 Naproxen NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

45 Nateglinide Oral hypoglycemic Meglitinide Insulinotropic

46 Naltrexone Opioid antagonist

47 Nedocromil Mast cell stabilizer Inhibits release of mast cell mediators Used prophylactically in asthma

48 Neomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation Topical

49 Neostigmine Anticholinesterase Vasodilator Treatment for myaesthenia gravis Promotes defecation and urination Bronchoconstrictor

50 Netilmicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

51 Nevirapine Antiretroviral Non-nucleoside reverse transcriptase inhibitor (NNRTI)

52 Nicardipine Antihypertensive Calcium channel blocker

53 Nicotine Cholinomimetic Drug of abuse Nicotinic receptor agonist (skeletal muscle contraction) Stimulant Smoking cessation medication

54 Nicotinic acid Antihyperlipidemic Inhibition of VLDL secretion (?)

55 Nifedipine Antihypertensive Antianginal Calcium channel blocker

56 Nifurtimox Tropical antiparasitic Treatment of South American Trypanosomiasis; Chagas disease

57 Nisoldipine Antihypertensive Calcium channel blocker

58 Nitrendipine Antihypertensive Calcium channel blocker

59 Nitrofurantoin Urinary tract antiseptic Reduction leads to intermediates that damage DNA

60 Nitroglycerine Venodilator Antianginal

61 Nitroprusside Vasodilator Antihypertensive

62 Nitrous oxide General anaesthetic Inhaled anaesthetic

63 Nizatidine Antihistamine Antiulcer H 2 receptor antagonist

64 Norepinephrine Sympathomimetic Vasoconstrictor

65 Norethindrone Progestin 19-nor testosterone analogue Combination oral contraceptive

66 Norethynodrel Progestin 19-nor testosterone analogue Combination oral contraceptive

67 Norfloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase

68 Norgestimate Progestin 19-nor testosterone analogue Combination oral contraceptive

69 Norgestrel Progestin 19-nor testosterone analogue Combination oral contraceptive

70 Nortriptyline Tricyclic antidepressant (TCA)

71 NPH insulin Hormone Insulin analogue Intermediate acting

72 Non-steroidal Anti-inflammatory Drugs (NSAIDs) Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitors

73 Nystatin Antifungal Polyene antibiotic Binds to ergosterol & alters permeability Topical

74 Octreotide Somatostatin analogue Peptide hormone inhibitor Decreases growth hormone secretion Decreases gastric and pancreatic secretions

75 Olsalazine NSAID (salicylate) Treatment of IBD

76 Omeprazole/esomeprazole Antiulcer H + /K + ATPase inhibitor

77 Ondansetron Antiemetic 5HT 3 receptor antagonist

78 Organic antimonials Tropical antiparasitic Treatment of Leishmaniasis sodium stibogluconate meglumine antimonate

79 Oseltamivir Antiviral Inhibits neuraminidase and decreases viral release Treatment of Influenza A & B

80 Oxacillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking

81 Oxazepam Sedative/hypnotic Anxiolytic Benzodiazepine Acts on GABA A receptor complex

82 Oxybutinin Anticholinergic Muscarinic receptor antagonist Prevents urination

83 Oxycodone Analgesic Opioid agonist

84 Oxytetracycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

85 Oxytocin Hypothalamic (posterior pituitary) hormone Uterine stimulant

86 Paclitaxel Antineoplastic Natural product Plant alkaloid (taxane)

87 Palivizumab Antiviral Monoclonal antibody against the surface of respiratory syncytial virus

88 Pamidronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption

89 Pancuronium Paralytic Paralyzes skeletal muscles

90 Pantoprazole Antiulcer H + /K + ATPase inhibitor

91 Para-aminosalicylic acid Antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Secondary TB drug

92 Paraldehyde Sedative/Hypnotic

93 Parathyroid hormone Hormone Maintains plasma Ca 2+ concentrations

94 Paromomycin Antiparasitic Aminoglycoside antibiotic Treatment of protozoal infections

95 Pectin Antidiarrheal

96 Penbutolol Sympatholytic  adrenergic antagonist Antihypertensive Bronchoconstrictor

97 Penciclovir Antiherpes Purine analog Phosphorylated to inhibitor of viral DNA polymerase

98 Penicillins  lactam antibiotics Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan

99 Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Acid labile Inhibits peptidoglycan cross-linking

100 Penicillin V Penicillin antibiotic Cell wall synthesis inhibitor More acid resistant than Penicillin G Inhibits peptidoglycan cross-linking

101 Pentamidine Tropical antiparasitic Treatment of African Trypanosomiasis


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