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Cool BaRC Web Tools Prat Thiru. BaRC Web Tools We have.

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Presentation on theme: "Cool BaRC Web Tools Prat Thiru. BaRC Web Tools We have."— Presentation transcript:

1 Cool BaRC Web Tools Prat Thiru

2 BaRC Web Tools http://iona.wi.mit.edu/bio/tools/bioc_tools.html http://iona.wi.mit.edu/bio/tools/bioc_tools.html We have tools for: General Analysis and File Utilities Genomics EntrezGene/RefSeq/UniGene/SGD/GenBank annotation Homology (Orthology) Converting IDs between databases Functional Analysis Visualization

3 General Analysis and File Utilities Venn Diagram Generator Show the number of items shared and unique between two sets http://jura.wi.mit.edu/bioc/tools/venn.html

4 General Analysis and File Utilities Compare Two Lists Find what is common and unique between two lists NM_126167 NM_126167 NM_126168 NM_322122 XM_322082 NR_210999 XM_322084 NR_001321 NM_126168 http://iona.wi.mit.edu/bell/compare.html

5 General Analysis and File Utilities Redundant List Analysis Count the number of occurrences in a list NM_126167 NM_126168 XM_322082 XM_322084 NR_001321 NM_126168 http://iona/cedrone/redundant/

6 General Analysis and File Utilities Submatrix Selector Select specific rows and columns in a file http://iona.wi.mit.edu/bell/submatrix_selector/

7 Genomics Genomic Sequence Extractor Retrieve sequence up/down stream for a list of genomic location(s) http://iona.wi.mit.edu/bell/extract_custom.html

8 Genomics RefSeq Regulatory Extractor Retrieve regions around transcription start or end site http://iona.wi.mit.edu/bell/refseq_extractor.html

9 Genomics Merge Overlapping Genome Regions Collapse overlapping regions into a single region http://iona.wi.mit.edu/bell/merge_regions/merge_regions.html

10 EntrezGene/RefSeq/UniGene/SGD/GenBank annotation Entrez Gene IDs  info Get information for a list of Entrez Gene IDs http://iona.wi.mit.edu/walker/webtools/locuslink-db-0.html

11 EntrezGene/RefSeq/UniGene/SGD/GenBank annotation Extract UTRs and/or CDS regions from GenBank sequences Retrieve UTRs/CDS from GenBank flat file http://iona.wi.mit.edu/bell/utrs/

12 Homology (Orthology) Find orthologous Ensembl IDs http://iona.wi.mit.edu/bell/homology/ensembl.html http://iona.wi.mit.edu/bell/comparative/

13 Converting IDs between Databases Entrez Gene IDs  Ensembl IDs Convert gene ids from Entrez to Ensembl http://iona.wi.mit.edu/bell/locuslink-db-7.html 

14 Functional Analysis Map Genes to Pathways http://iona.wi.mit.edu/yuan/gene2pathway/ Determine which pathway genes might be involved from different databases.

15 Functional Analysis Identify over-represented GO terms in a gene set http://iona.wi.mit.edu/yuan/go_anno/ Find out which GO categories are over-represented in the GO terms

16 Functional Analysis Walk up GO ontologies to get more general "induced" terms http://iona.wi.mit.edu/bell/go/ Find more general GO terms

17 Functional Analysis Tabulate the number of codons in sequence data http://iona.wi.mit.edu/gurdziel/CodonCounter/CodonCounter.html Determine codon usage in a sequence

18 Visualization Protein Sequence Visualization Tool http://iona.wi.mit.edu/cgi-bin/walker/draw_enrichment.pl Color codes amino acids

19 Visualization Sequence Word Viewer http://iona.wi.mit.edu/rodriguez/wordview/ Display occurrences of a motif Seq 55 MTKVYANSIQQHLCLDSLTGPVRSVLTQGTTAEKERVVDRIALLERCLDP SNSLPPVRSVLTQGTTAEKVQLVVSCLGVVCSIICLALGIAAAAVTAKRL VAVAVATILAVALLVVAGLLFSGVLCSPVSVLAASLFFGVGAFLLGGALV GGVLTTEAVTRERLHRSQTLMWNNLCCKTAEVEQKISTASANAKSNDKTR KLGE Seq 200 MECVKQLCRNHLCLDSLTGPVRSVLTQGTTAEKVQLVVSCLGVVCSIICL ALGIAAAAVGVSCSGFAIGLGVIAILLGIVLFAISALDVLEDHGLVGAAS LFFGVGAFLLGGALVGGCPFKLPCKSSPANEPTVQFFKGKNGSADKVILV TQ

20 TargetScan http://www.targetscan.org/ Find predicted targets of miRNA

21 Need a tool? Let us know! wibr-bioinformatics@wi.mit.edu


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