1. The Work of Gregor Mendel

2. Essential Question:  Describe Mendel’s studies and conclusions about inheritance.  Describe what happens during segregation.

3. Gregor Mendel = Father of Genetics Worked with garden pea plant 1857

4. Mendel’s Experiments Peas are a “model system.” Started with “true breeding” plants Trait: specific characteristic (e.g., seed color, plant height) of an individual Hybrid: created from cross of true-breeding individuals Small, easy to grow. Makes them convenient to study. Help explain how organisms inherit traits

5. Pollination and Fertilization in Plants Male part Female part Plants have the ability to self-pollinate (self-fertilize) because they have both reproductive parts.

6. Cross-Pollination Pollen Taking pollen from one plant and using it to fertilize the eggs of another plant

7. Pea Characteristics of Mendel’s peas Mendel studied these characteristics to observe patterns in traits across generations.

8. Mendel’s Crosses When Mendel crossed plants with contrasting traits, the hybrid offspring showed traits of only one parent.

9. Dominant and Recessive Traits Yellow seed color is to green seed color. Green seed color is to yellow seed color. dominant recessive When a yellow pea plant is crossed with a green pea plant, the resulting offspring are yellow.

10. Principle of Dominance Some alleles are dominant, some recessive. An organism with at least one dominant allele will exhibit that trait. An organism with a recessive allele will exhibit the trait only in the absence of a dominant allele. dominantrecessivedominant

11. Genes and Alleles Traits (seed shape, seed color) are determined by genes. Genes: passed from one generation to the next; genetic code that determines an individual’s characteristics Forms of traits (yellow/green, round/wrinkled) are called alleles. Alleles: the different forms of a gene. Characteristics such as pod color are determined by. Yellow and green pod colors are determined by. The allele for green pods is to the allele for yellow. genes alleles dominant

12. The P and F 1 Generation P 1 generation F 1 generation True-breeding Hybrids Let’s figure out how we can predict the F 1 gen from the P 1 gen.

13. Monohybrid Cross = One Trait “Height” “True Breeding” = Homozygous Tall Pea x Short Pea TT x tt T = Dominant t = Recessive X “Homozygous Dominant” “Homozygous Recessive”

14. Heterozygous and Homozygous Homozygous: has two identical alleles for a gene Heterozygous: has two different alleles for a gene Which are: homozygous? heterozygous? 1 2 3 1, 4 2, 3 4

15. 1 st LAW OF HEREDITY “Law of Segregation” = –The 2 alleles for each trait must separate when gametes (sperm/egg) are formed. - A parent passes on, at random, only one allele for each trait to each offspring A  a

16. Segregation Segregation: separation of alleles during gamete formation

17. Segregation Random Fertilization

18. The Formation of Gametes Eggs and sperm Fertilization

19. Making a Punnett Square Combine gamete genotypes Gametes for a parent along one side Possible gametes A cross of birds: Beak size (B, b)

20. Generations P1 = Parent Plants -True breed Tall x True breed Short = First Generation (children) F1 TT x tt What’s the probability that the offspring will be tall? ________ Short? _______ Genotype of offspring? ______________ Genotype=genetic makeup of organism Phenotype of offspring? _____________ Phenotype=physical characteristics

21. Law of Probability “Rules of Chance” “Odds” 20:1 5% 10:1 10% 2:1 50% Numerator = winner Denominator = # horses 1/12 1:12 “odd” 8% “chance”

22. Probability? “Chance” of getting a tail? “Chance” of getting snake eyes on two dice?

23. Male: Female XYXX ½ 1:2 odd Boy 1:2 odd Girl 50% chance Survey Large Number 1:1 “Chance” of getting a boy?

24. Dominant = Trait Observed Recessive = Trait that disappeared Tall = Dominant (T) Short = Recessive (t) Alleles: TT = Tall Tt = Tall tt = Short PhenotypeGenotype Can’t always know an organisms genotype by looking at its phenotype?

25. TT tt T t TtTt Homozygous Dominant Homozygous Recessive Heterozygous

26. Tt x Tt 3 Tall and 1 Short T t F1 F2 TtTt Combination of Letters/Alleles? TtTt Change of colors to follow the parental alleles:

27. The F 2 Generation – created from a cross of two F 1 generation offspring. What proportion of F 2 offspring were short? What proportion of F 2 offspring were tall? 1/4 3/4