1. 240 Enbrel Cases 70 Deliveries 48 Ongoing Pregnant 49 Abortions 73 Failures Conception Rate 70% Failure Rate 30% Ongoing Preg R 71% Abortion Rate29%

2. 240 Enbrel Cases: OB Hx 48% RSA [>2 Abortions ] 30% 1-2 Abortions 22% Infertility [0 abortions ]

3. 240 Cases : Reprod. Rates Infertile [0Ab] CR 49% AR 27% <3Abortions CR 67% AR 12% RSA [>2Ab] CR 81% AR 29% CR = Conception Rate; AR = Abortion Rate

4. 70 Enbrel Deliveries MEANS Mom's age 34.4 Gravidity2.9 Parity0.4 #Abortions2.5 #IVF failure0.7 Enbrel Intake Preconception 2.8 mo Postconception2.8 mo

5. 80 Enbrel Babies Ave. GA 37.4wk Ave. BWt6.4 lbs 10 twins, 1 triplet 73% Term 27% Preterm Ave GA 34wk Range: 29-36.5wk Ave BWt

6. Enbrel after Failed ImmunoTx 8Deliveries 1 Ongoing Pregnant 3 Abortions 1 Failures

7. 35 Enbrel: >3IVF failures Hx Delivered 6 Pregnant 8 (16 conceived by IVF) Abortions 2 Failures 22 Conception Rate 49% Abortion Rate 12%