1. Genetic Disorders »By: Mr. Robey

7. Each egg and each sperm

9. Causes of Genetic Disorders: Radiation or chemicals cause changes in the order of DNA “letters” -Mutated DNA can be inherited by the child (in the sperm or egg) -Damage can occur to the egg or sperm producing cells (ovaries or testes) -Damage can occur to the sperm or egg -Damage can occur to the embryo after conception

10. Types of DNA mutations: A genetic disorder can result when: A single gene is mutated Several genes are mutated, all working together One or more genes is missing An entire chromosome is missing There is an extra chromosome

11. Skin Disorders

12. Albinism

13. Malignant Melanoma

14. Xeroderma Pigmentosum

15. Bloom Syndrome

16. Porphyria

17. Amyloidosis

18. Eye Disorders

19. Color blindness

20. Retinitis Pigmentosum

21. Retinoblastoma

22. Bone/Joint Disorders

23. Multiple Exostosis

24. Osteogenesis Imperfecta

25. Fibrodysplasia Ossificans Progressiva

26. Apert Syndrome

27. Edward’s Syndrome

28. Polydactyly

29. Muscle Disorders

30. Muscular Dystrophy

31. Refsum Disease

32. Hair Disorders

33. Male Pattern Baldness

34. Alopecia

35. Blood Disorders

36. Sickle Cell Disease

37. Hemophilia

38. Severe Combined Immunodeficiency

39. Polycystic Kidney Disease

40. Mental Disorders

43. Down Syndrome

44. Angelman Syndrome

45. Cri du Chat Syndrome

46. Growth Disorders

47. Pituitary Dwarfism

48. Diastrophic Dysplasia

49. Premature Aging Disorders

50. Progeria

51. Cockayne Syndrome