1. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings C h a p t e r 20 The Cardiovascular System: Blood PowerPoint ® Lecture Slides prepared by Agnes Yard and Michael Yard Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

2. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following leukocytes have deep red granules and bi- lobed nuclei and increase in numbers dramatically during an allergic reaction or parasitic infection? a. monocytes b. basophils c. lymphocytes d. eosinophils

3. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following are primary lymphoid organs? a. spleen and thymus b. bone marrow and thymus c. spleen and bone marrow d. thymus and tonsils

4. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following cells form rouleaux? a. platelets b. monocytes c. leukocytes d. erythrocytes

5. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings On average, there are ________ of whole blood in the cardiovascular system of an adult man, with a slightly ________ pH. a. 2 – 3 liters, neutral b. 2 – 3 liters, alkaline c. 5 – 6 liters, alkaline d. 5 – 6 liters, neutral

6. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Individual platelets usually circulate for how long before being removed by phagocytes? a. 10 – 12 hours b. 1 – 2 months c. 3 – 4 weeks d. 10 – 12 days

7. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following conditions refers to a low number of lymphocytes? a. leukocytosis b. lymphocytosis c. thrombocytopenia d. lymphopenia

8. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings An abnormally low hematocrit value likely indicates which of the following? a. polycythemia b. anemia c. hypovolemia d. leukopenia

9. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings The porphyrin ring surrounding a single ion of iron, which reversibly binds to oxygen, in a hemoglobin molecule is called: a. heme b. alpha (α) chain 1 c. globular protein d. beta (β) chain 2

10. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings What is the primary site of blood cell formation in the adult? a. red bone marrow b. thymus c. yellow bone marrow d. spleen

11. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following cells form plasmocytes that secrete antibodies? a. NK cells b. T cells c. B cells d. monocytes

12. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following is not a function of blood? a. stabilization of body temperature b. prevention of fluid losses via the clotting reaction c. stabilization of the pH and electrolyte composition of intracellular fluids throughout the body d. distribution of nutrients absorbed from the digestive tract or released from storage in adipose tissue or the liver

13. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following leukocytes are two to three times the diameter of a typical erythrocyte and are known as “free macrophages” outside the bloodstream? a. monocytes b. lymphocytes c. eosinophils d. basophils

14. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings A mature megakaryocyte gradually loses all of its cytoplasm, producing ________ platelets before its nucleus is engulfed by phagocytes and broken down for recycling. a. 500 b. 1,000 c. 4,000 d. 10,000

15. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following statements regarding blood types is false? a. The surface antigens are glycoproteins, or glycolipids, whose characteristics are genetically determined. b. The blood of a Type A, Type B, or Type O individual always contains antibodies that will attack foreign surface antigens. c. A typical white blood cell plasmalemma contains a number of surface antigens, or agglutinogens, exposed to the plasma. d. An individual’s blood type is determined by the presence or absence of specific components in erythrocyte cell membranes.

16. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings “Serum” is plasma without: a. fibrinogen b. albumins c. globulins d. platelets

17. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following cells are examples of granular leukocytes? a. eosinophils and monocytes b. neutrophils and eosinophils c. neutrophils and lymphocytes d. eosinophils and lymphocytes

18. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following components of whole blood function in the clotting response? a. platelets b. red blood cells c. albumins d. white blood cells

19. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings In leukocytosis, a white-blood-cell count of more than _________ per μl usually indicates a serious disorder. a. 30,000 b. 25,000 c. 20,000 d. 10,000

20. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following statements regarding lymphocytes is false? a. Lymphocytes are slightly smaller than red blood cells and account for 50 – 60 percent of the white blood cell population. b. Lymphocytes are responsible for specific immunity. c. Lymphocytes have very little cytoplasm, with just a thin halo around a relatively large round, purple- staining nucleus. d. Blood lymphocytes represent a minute segment of the entire lymphocyte population.

21. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Myeloid stem cells do not give rise to: a. erythrocytes b. monocytes c. lymphocytes d. b and c

22. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following statements regarding erythrocytes (RBCs) is/are false? a. RBCs are produced in bone marrow. b. RBCs do not have a nucleus, mitochondria, or ribosomes. c. RBCs have a 180-day life expectancy. d. None of the above is false.

23. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Basophils, eosinophils, and neutrophils arise from: a. proerythroblasts b. lymphoblasts c. myeloblasts d. monoblasts

24. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following leukocytes are produced in bone marrow and assist mast cells of tissues in producing inflammation? a. neutrophils b. monocytes c. eosinophils d. basophils

25. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Which of the following is/are produced under hypoxic conditions, and stimulate(s) increased rates of cell division in erythrocytes? a. erythropoietin (EPO) b. colony-stimulating hormone c. vitamin B 12 d. a and c

26. Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Plasma proteins make up what percentage of overall plasma composition? a. 15% b. 7% c. 35% d. 60%