1. Questions for the audience Dept of Pharmacology, PIMS

2. 1. Which drug is obtained from this plant?

3. Artemisinins Answer

4. a. a.Halofantrine b. b.Artemether c. c.Atovaquone d. d.Primaquine 2. Which of the following antimalarial drug is known to prolong QT interval?

5. a. Halofantrine Answer

6. a. a.Chloroquine b. b.Mefloquine c. c.Doxycycline d. d.Proguanil 3. For a person visiting an area with multidrug resistant malaria which of the following drugs is preferred for malaria prophylaxis

7. c. Doxycycline Answer

8. 4. Blackwater fever is a fatal complication seen with a. a.Mefloquine b. b.Quinine c. c.Chloroquine d. d.Primaquine

9. b. Quinine Answer

10. 5. Drug used to eradicate hypnozoites in liver a. a.Artemisinin b. b.Proguanil c. c.Primaquine d. d.Atovaquone

11. c. Primaquine Answer

12. 6.Plasmodial resistance to chloroquine is due to a. a.Change in the structure of receptor b. b.reduced drug accumulation within food vacuole c. c.Induction of metabolizing enzymes d. d.Increase in DNA repair mechanisms

13. b. reduced drug accumulation within food vacuole of the parasite Answer

14. 7. Drug recommended for oral treatment of uncomplicated malaria by chloroquine resistant P. falciparum is a. a.Atovaquone b. b.Quinine c. c.Proguanil d. d.Iodoquinol

15. b. Quinine Answer