1. Developing a community of Interdisciplinary Scholars at The University of Chicago Julie Feder Institute for Biophysical Dynamics 5 March 2006

2. Institute for Biophysical Dynamics In Center for Integrative Science Computation Institute Consortium for Nanoscience Research

3. *Specialization in Cellular & Molecular Biology *Specialization in Ecology and Evolution *Specialization in Immunology Specialization in Genetics Specialization in Microbiology Specialization in Neuroscience *requires research experience Biological Sciences Collegiate Division (BSCD)

4. Faculty Undergraduates in Natural Sciences Biological Sciences Collegiate Division (BSCD) MGCB, BMB, Ecol/Evol, OBA, NPP, Clinical Departments doing basic science Physical Sciences Collegiate Division (PSCD) Chemistry, Geophysical Sciences, Physics, Astronomy and Astrophysics math, CS, Stat

5. HHMI Summer Undergraduate Research Fellowship HHMI Summer Program in Neuroscience and Neuroengineering *Physical and Chemical Biology Training Program (PCBio) *Beckman Scholars Program in Molecular Sciences Research Opportunities

6. Why Chicago Teacher of Teachers Laboratory for Educational Experimentation Interdisciplinary history Outstanding Students Highly Ranked Departments

7. Cultural Barriers at Chicago Learning about biological v. Physical Sciences Understanding/Evaluating Science

8. Program Goals Transform the culture at Chicago Tribal to Interdisciplinary Bring together the Community Physical Sciences Faculty Institutes Medical School Basic Sciences

9. Why Undergraduates? Early Intervention Curriculum/Educable Curious Passionate Outcomes & Impact

10. Approach Community of Scholars Create Links between Students and Faculty Empowering the Fellows for Independence

11. Student Centered Program Proposals come from Students, not PI Competitively vetted Stipends for Fellows Opportunity to interact with students, not Mentors

12. Community of Scholars Weekly Meetings Oral presentations Open discussion Retreat with ID Graduate Students Promoting long-term Relationships

13. Faculty director’s Role Alternative, Independent Shared Commitment from parallel history Non-conformists Rapid Response Connected sideways and upwards

14. Empowering the Fellows for Independence Personal relationships/directors as Mentors Fellows Impact Program Evolution Generations passing on Culture

15. Student Selection Based on student-generated proposal Evaluated by two faculty members (from PSD and BSD) Fellows participate in: Life in BSD lab weekly Student seminars Spring quarter-biophysical Discussions

16. Time line Application deadlineEnd of Winter Q Student Interviews Beginning of Spring Q Awards announcedMid April Summer Program Beginsmid June Summer Program endsmid August

17. Mentors: Biologists paired with quantitative scientist Computer Sciences Chemists Physicists Statisticians (Mathematicians)

18. Why Roadmap initiative NIH conservative, Tribal, Segmented High Risk, High Reward Broadly Cross-disciplinary Math/Stat to Therapy

19. Quantitative biology How much Math do biologists need to know Biology is increasing quantitative importance of models in biology large data sets generated by genomic/proteomic approaches

20. Mathematical Methods For Biological Scientists I linear Algebra, DE, Dynamical Systems ii Partial Differentials, Vector spaces, Fourier Transformations III probability, PC Analysis, Stochastic processes Lab component

21. Thanks! Steve Kron Associate Professor Molecular Genetics & Cell Biology All of you