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Dose and Time-Dependent Effects of Cyclooxygenase-2 Inhibition on Fracture-Healing by Ann Marie Simon, and J. Patrick O'Connor J Bone Joint Surg Am Volume.

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Presentation on theme: "Dose and Time-Dependent Effects of Cyclooxygenase-2 Inhibition on Fracture-Healing by Ann Marie Simon, and J. Patrick O'Connor J Bone Joint Surg Am Volume."— Presentation transcript:

1 Dose and Time-Dependent Effects of Cyclooxygenase-2 Inhibition on Fracture-Healing by Ann Marie Simon, and J. Patrick O'Connor J Bone Joint Surg Am Volume 89(3):500-511 March 1, 2007 ©2007 by The Journal of Bone and Joint Surgery, Inc.

2 Histograms illustrating the effects of celecoxib dose on fracture-healing. Ann Marie Simon, and J. Patrick O'Connor J Bone Joint Surg Am 2007;89:500-511 ©2007 by The Journal of Bone and Joint Surgery, Inc.

3 Histograms illustrating the effects of celecoxib treatment duration on fracture-healing. Ann Marie Simon, and J. Patrick O'Connor J Bone Joint Surg Am 2007;89:500-511 ©2007 by The Journal of Bone and Joint Surgery, Inc.

4 Histograms illustrating the effects of delayed celecoxib treatment on fracture-healing. Ann Marie Simon, and J. Patrick O'Connor J Bone Joint Surg Am 2007;89:500-511 ©2007 by The Journal of Bone and Joint Surgery, Inc.

5 Histograms illustrating that nonsteroidal anti-inflammatory drug treatment reduces fracture callus prostaglandin levels. Ann Marie Simon, and J. Patrick O'Connor J Bone Joint Surg Am 2007;89:500-511 ©2007 by The Journal of Bone and Joint Surgery, Inc.

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