1. Brendan M. Duggan, Ph.D. Research Interests Applications of NMR Natural products structure elucidation Obtaining structurally useful information Increasing throughput Biomolecular structure and dynamics Solution structure determination Quantifying dynamics, e.g. folding, diffusion Increasing throughput Molecular dynamics simulations Integrating experimental NMR data with MD

2. Core Expertise Two 600 MHz (14.1 Tesla) Avance III Bruker Spectrometers Two cryoprobes – 5mm and 1.7mm Sample changer – 60 samples Protein and small molecule NMR NMR experimental design NMR data processing and analysis Amber MD simulations Bioinformatic sequence analysis

3. Proposed Collaborations with SSPPS Faculty Bill Gerwick Reducing NMR data acquisition time Ted Molinski Increasing sensitivity Brad Moore Extracting additional structurally useful information sopnmr.ucsd.edu sopnmr@ucsd.edu