2. 03-05 W. W. Norton

5. 02-11ab

7. 02-28

8. 02-29 Adapted from Kandel, E.R. Schwartz, J.H., and Jessell, T.M. (Eds.), Principles of Neural Science, 3rd edition. Norwalk, Connecticut: Appleton & Lange, 1991. Copyright © 1991 by Appleton & Lange.

9. Important Neurotransmitters endorphin acetylcholine dopamine norepinephrin e serotonin Gaba

10. Endorphin Relieves pain Responsible for “joggers high”

11. Acetylcholine Important in memory Transmitter in the hippocampus Transmitter at the neuro-muscular junction.

12. Acetyl CoA + Choline Acetylcholine notes: Vitamin B5 makes up part of Acetyl CoA. curare (a dart poison) blocks acetylcholine

13. Dopamine There is too little in Parkinson disease There is too little in tardive dyskinesia

14. Norepinephrine There is too little in depression Increases alertness

15. Tyrosine L-dopa dopamine norepinephrine Phenylalanine

16. 02-34 W. W. Norton

17. MAO = monoamine oxidase MAO Breaks down: dopamine norepinephrine serotonin An MAO inhibitor prevents the breakdown of these neurotransmitters.

18. Serotonin Controls sleep onset There is too little in depression Affected by the prescription drugs prosac and zoloft

19. tryptophan serotonin

20. GABA Valerian root affects GABA GABA is available as a free from amino acid Can act as a tranquilizer Prescription