1. Blood

2. Components of Blood Whole blood RBCs WBCs
Platelets: cell fragments that aid in clotting
Plasma
90% water (allows materials to dissolve)
Amino acids, glucose, hormones, vitamins, salts, waste
Concentrations allows diffusion in/out of blood stream

3. Click picture to play

4. Platelets Form clots when bleeding
Proteins form a web to trap cells & platelets

5. White Blood Cells Remove foreign invaders & dead cells
Able to move through body tissue

6. Red Blood Cells Produced from stem cells in bone marrow
Lose nucleus as they mature
Transport O2 to cells; remove CO2
O2 binds to hemoglobin proteins
Dead cells filtered by liver & spleen

7. Sickle Cell
Normal

8. ABO Blood Groups
Proteins on blood cells (antigens) determine blood type
Antigens:
proteins on cells that identify cells as foreign or natural
on the surface of RBCs
Antibodies:
proteins from WBCs to attack invaders
in the blood plasma

9. Group A blood A antigens on the surface of your RBCs
B antibodies in your blood plasma

10. Group B blood B antigens on the surface of your RBCs
A antibodies in your blood plasma

11. Group AB blood A and B antigens on the surface of your RBCs
no A or B antibodies at all in your blood plasma

12. Group O blood No A or B antigens on the surface of your RBCs
both A and B antibodies in your blood plasma

13. If you have type A blood, can you receive: Type B blood from a donor?
Type AB blood from a donor?
Type O blood from a donor?

14. If you have type B blood, can you receive:
Type A blood from a donor?
Type AB blood from a donor?
Type O blood from a donor?

15. If you have type AB blood, can you receive:
Type A blood from a donor?
Type B blood from a donor?
Type O blood from a donor?

16. If you have type O blood, can you receive: Type A blood from a donor?
Type B blood from a donor?
Type AB blood from a donor?

19. Rh Factors Rh+ Rh- Protein found in blood Can receive Rh+ or Rh- blood
Lack protein in blood
Only receive Rh- blood

20. Francis was just in a bad accident and lost a lot of blood
Francis was just in a bad accident and lost a lot of blood. He is blood type B+. Can you help save him?

21. Blood type B+ Antigens: Which does he have? A B Rh
Antibodies: Which does he have? A B Rh

22. Vein Can we give Francis B+ blood? Will Francis’ A antibodies attack?
No.
Can he accept B+ blood?
Yes. You can always accept your own blood type.
Vein
A antibody
A antibody
A antibody
A antibody

23. Vein Can we give Francis B- blood? Will Francis’ A antibodies attack?
No.
Can he accept B- blood?
Yes. Since the A antibodies only attack A antigens, there is no danger.
Vein
A antibody
A antibody
A antibody
A antibody

24. Vein No. Francis’ A antibodies will attack the A antigens.
Can we give Francis A+ blood?
Will Francis’ A antibodies attack?
Yes.
Can he accept A+ blood?
No. Francis’ A antibodies will attack the A antigens.
Vein
A antibody
A antibody
A antibody
A antibody

25. Vein No. Francis’ A antibodies will attack the A antigens.
Can we give Francis A- blood?
Will Francis’ A antibodies attack?
Yes.
Can he accept A- blood?
No. Francis’ A antibodies will attack the A antigens.
Vein
A antibody
A antibody
A antibody
A antibody

26. Vein No. Francis’ A antibodies will attack the A antigens.
Can we give Francis AB+ blood?
Will Francis’ A antibodies attack?
Yes.
Can he accept AB+ blood?
No. Francis’ A antibodies will attack the A antigens.
Vein
A antibody
A antibody
A antibody
A antibody

27. Vein No. Francis’ A antibodies will attack the A antigens.
Can we give Francis AB- blood?
Will Francis’ A antibodies attack?
Yes.
Can he accept AB- blood?
No. Francis’ A antibodies will attack the A antigens.
Vein
A antibody
A antibody
A antibody
A antibody

28. Can we give Francis O+ blood?
Will Francis’ A antibodies attack?
No.
Can he accept O+ blood?
Yes. Since the A antibodies only attack A antigens, there is no danger.
Vein
A antibody
A antibody
A antibody
A antibody

29. Can we give Francis O- blood?
Will Francis’ A antibodies attack?
No.
Can he accept O- blood?
Yes. Since the A antibodies only attack A antigens, there is no danger.
Vein
A antibody
A antibody
A antibody
A antibody

30. Blood Type Internet Lesson

31. Sebastian was just involved in an accident at work and lost a lot of blood. He is blood type A-. Can you help save him?

32. Blood type A- Antigens: Which does he have? A B Rh
Antibodies: Which does he have? A B Rh

33. This person has A- blood type because of the A antigens
This person has A- blood type because of the A antigens. Can he accept A- blood?
Yes. You can always accept your own blood type.
Vein
B antibody
B antibody
Rh antibody
Rh antibody

34. This person has A- blood type because of the A antigens
This person has A- blood type because of the A antigens. Can he accept A+ blood?
No. Sebastian’s Rh antibodies will attack the Rh antigens.
Vein
B antibody
B antibody
Rh antibody
Rh antibody

35. This person has A- blood type because of the A antigens
This person has A- blood type because of the A antigens. Can he accept B- blood?
No. Sebastian’s B antibodies will attack the B antigens.
Vein
B antibody
B antibody
Rh antibody
Rh antibody

36. This person has A- blood type because of the A antigens
This person has A- blood type because of the A antigens. Can he accept B+ blood?
No. Sebastian’s B and Rh antibodies will attack the B and Rh antigens.
Vein
B antibody
B antibody
Rh antibody
Rh antibody

37. This person has A- blood type because of the A antigens
This person has A- blood type because of the A antigens. Can he accept AB- blood?
No. Sebastian’s B antibodies will attack the B antigens.
Vein
B antibody
B antibody
Rh antibody
Rh antibody

38. This person has A- blood type because of the A antigens
This person has A- blood type because of the A antigens. Can he accept AB+ blood?
No. Sebastian’s B and Rh antibodies will attack the B and Rh antigens.
Vein
B antibody
B antibody
Rh antibody
Rh antibody

39. This person has A- blood type because of the A antigens
This person has A- blood type because of the A antigens. Can he accept O- blood?
Yes. Sebastian’s antibodies do not attack these antigens.
Vein
B antibody
B antibody
Rh antibody
Rh antibody

40. This person has A- blood type because of the A antigens
This person has A- blood type because of the A antigens. Can he accept O+ blood?
No. Sebastian’s Rh antibodies will attack the Rh antigens.
Vein
B antibody
B antibody
Rh antibody
Rh antibody

41. Blood type AB+ Antigens: Which does they have? A B Rh
Antibodies: Which does they have? A B Rh

42. Blood type O+ Antigens: Which does they have? A B Rh
Antibodies: Which does they have? A B Rh

43. Blood type AB- Antigens: Which does they have? A B Rh
Antibodies: Which does they have? A B Rh

44. Blood type B+ Antigens: Which does they have? A B Rh
Antibodies: Which does they have? A B Rh

45. Blood type O- Antigens: Which does they have? A B Rh
Antibodies: Which does they have? A B Rh