1. Condition National Cost Heart disease $90.9 B Cancer 71.4 Trauma-related 67.3 Mental disorders 59.9 Osteoarthritis 56.2 Hypertension 47.3 Diabetes 45.5 COPD, Asthma 44.5 Hyperlipidemia 38.5 Back problems 34.6 1O most costly medical conditions Soni, A. Top 10 Most Costly Conditions among Men and Women, 2008: Statistical Brief #331. July 2011. AHRQ,. http://www.meps.ahrq.gov/mepsweb/data_files/publications/st331/stat331.pdf

2. Medical & Pharmacy Costs $3,376 PEPY 25% 75% Personal Health Costs Medical Care Pharmacy Productivity Costs Presenteeism Overtime Turnover Temporary Staffing Administrative Costs Replacement Training Off-Site Travel for Care Customer Dissatisfaction Variable Product Quality Total Costs = $13,504 PEPY Absenteeism Health-Related Productivity Costs $10,128 PEPY Short-term Disability Long-term Disability Sources: Edington DW, Burton WN. Health and Productivity. In McCunney RJ, Editor. A Practical Approach to Occupational and Environmental Medicine. 3rd edition. Philadelphia, PA. Lippincott, Williams and Wilkens; 2003: 40-152 and Loeppke, R., et al. Health and Productivity as a Business Strategy. Journal of Occupational and Environmental Medicine. Vol 49, No. 7, July, 2007. Pages 712-721 and the 2006 Mercer Employer Annual Survey; The Real Problem: The Full Cost of Poor Employee Health

3. Total Medical, Pharma&Productivity Costs -- per 1000/FTEs -- $300,000$100,000 $400,000 (HPBS – Phase 2 Employers) $200,000 Source: “Health and Productivity as a Business Strategy,” JOEM. Vol. 51, No. 4, April 2009 3

4. Use of Treatment Algorithms for Depression Treatment algorithms can help clinicians decide which treatment strategies to use. The data are fairly consistent in showing that algorithms result in not just better response rates, but improved patient satisfaction as well. An important factor may be that a care coordinator identifies patients who are not doing well and need to move to the next step in an algorithm. A critical question is whether the better outcomes are related to the use of the care coordinator. Trivedi, M. H., et al (2006). Journal of Clinical Psychiatry, 67(9), 1458-1465.