1. Chapter 23 - The Lymphoid System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction and Overview Structure of Lymphatic Vessels Lymphocytes Lymphoid Tissues Lymphoid Organs / Effects of Aging FINAL ROUND

2. Topic 1: $100 Question The lymphoid system: a. helps eliminate regional differences in the composition of interstitial fluid. b. produces, maintains, and distributes lymphocytes. c. provides an alternate route for the transport of hormones, nutrients, and waste products. d. All of the above. BACK TO GAME ANSWER

3. Topic 1: $100 Answer The lymphoid system: a. helps eliminate regional differences in the composition of interstitial fluid. b. produces, maintains, and distributes lymphocytes. c. provides an alternate route for the transport of hormones, nutrients, and waste products. d. All of the above. BACK TO GAME

4. Topic 1: $200 Question Which of the following statements concerning lymph is/are false? a. Lymph contains interstitial fluid, which resembles blood plasma, but with a higher concentration of proteins. b. Lymph contains macrophages of various types. c. Lymph contains lymphocytes, which are cells responsible for the immune response. d. None of the statements is false. BACK TO GAME ANSWER

5. Topic 1: $200 Answer Which of the following statements concerning lymph is/are false? a. Lymph contains interstitial fluid, which resembles blood plasma, but with a higher concentration of proteins. b. Lymph contains macrophages of various types. c. Lymph contains lymphocytes, which are cells responsible for the immune response. d. None of the statements is false. BACK TO GAME

6. Topic 1: $300 Question In order to maintain normal blood volume and eliminate local variations in the chemical composition of interstitial fluid, blood pressure at the ____ end of a systemic capillary tends to force water and solutes ____ the plasma. a. distal, out of b. proximal, into c. distal, into d. proximal, out of BACK TO GAME ANSWER

7. Topic 1: $300 Answer In order to maintain normal blood volume and eliminate local variations in the chemical composition of interstitial fluid, blood pressure at the ____ end of a systemic capillary tends to force water and solutes ____ the plasma. a. distal, out of b. proximal, into c. distal, into d. proximal, out of BACK TO GAME

8. Topic 1: $400 Question Which of the following are examples of secondary lymphoid structures? a. lymph nodes and tonsils b. lymph nodes and bone marrow c. bone marrow and thymus d. tonsils and thymus BACK TO GAME ANSWER

9. Topic 1: $400 Answer Which of the following are examples of secondary lymphoid structures? a. lymph nodes and tonsils b. lymph nodes and bone marrow c. bone marrow and thymus d. tonsils and thymus BACK TO GAME

10. Topic 1: $500 Question In which of the following structures are lymphocytes not produced and stored? a. spleen and thymus b. lymph nodes c. bone marrow d. A and C BACK TO GAME ANSWER

11. Topic 1: $500 Answer In which of the following structures are lymphocytes not produced and stored? a. spleen and thymus b. lymph nodes c. bone marrow d. A and C BACK TO GAME

12. Topic 2: $100 Question The ____ segment of the thoracic duct lies ____ to the vertebral column at the level of the second lumbar vertebrae. a. superior, anterior b. inferior, anterior c. superior, lateral d. inferior, posterior BACK TO GAME ANSWER

13. Topic 2: $100 Answer The ____ segment of the thoracic duct lies ____ to the vertebral column at the level of the second lumbar vertebrae. a. superior, anterior b. inferior, anterior c. superior, lateral d. inferior, posterior BACK TO GAME

14. Topic 2: $200 Question Superficial lymphatics are not found in, or do not collect lymph from, which of the following locations? a. the subcutaneous tissue next to the skin b. skeletal muscles and other organs of the neck, limbs and trunk c. the loose connective tissues of the mucous membranes lining the digestive, respiratory, urinary and reproductive tracts d. the loose connective tissues of the serous membranes lining the pleural, pericardial, and peritoneal cavities BACK TO GAME ANSWER

15. Topic 2: $200 Answer Superficial lymphatics are not found in, or do not collect lymph from, which of the following locations? a. the subcutaneous tissue next to the skin b. skeletal muscles and other organs of the neck, limbs and trunk c. the loose connective tissues of the mucous membranes lining the digestive, respiratory, urinary and reproductive tracts d. the loose connective tissues of the serous membranes lining the pleural, pericardial, and peritoneal cavities BACK TO GAME

16. Topic 2: $300 Question Which structure receives lymph from the inferior region of the abdomen, pelvis, and lower limbs through the lumbar and intestinal trunks? a. bronchomediastinal trunk b. jugular trunk c. cisterna chyli d. subclavian trunk BACK TO GAME ANSWER

17. Topic 2: $300 Answer Which structure receives lymph from the inferior region of the abdomen, pelvis, and lower limbs through the lumbar and intestinal trunks? a. bronchomediastinal trunk b. jugular trunk c. cisterna chyli d. subclavian trunk BACK TO GAME

18. Topic 2: $400 Question Which of the following are not lymphatic trunks? a. cervical trunks b. intestinal trunks c. lumbar trunks d. bronchomediastinal trunks BACK TO GAME ANSWER

19. Topic 2: $400 Answer Which of the following are not lymphatic trunks? a. cervical trunks b. intestinal trunks c. lumbar trunks d. bronchomediastinal trunks BACK TO GAME

20. Topic 2: $500 Question Which of the following structures empties into the venous system at or near the junction of the right internal jugular vein and subclavian vein? a. cisterna chyli b. cervical trunk c. right lymphatic duct d. bronchomediastinal trunk BACK TO GAME ANSWER

21. Topic 2: $500 Answer Which of the following structures empties into the venous system at or near the junction of the right internal jugular vein and subclavian vein? a. cisterna chyli b. cervical trunk c. right lymphatic duct d. bronchomediastinal trunk BACK TO GAME

22. Topic 3: $100 Question Which population of lymphocytes assists in the regulation and coordination of the immune response? a. B cells b. cytotoxic T-cells c. NK cells d. suppressor T cells BACK TO GAME ANSWER

23. Topic 3: $100 Answer Which population of lymphocytes assists in the regulation and coordination of the immune response? a. B cells b. cytotoxic T-cells c. NK cells d. suppressor T cells BACK TO GAME

24. Topic 3: $200 Question Which of the following cells become activated only if the same antigen appears in the body at a later date? a. cytotoxic T-cells b. memory T-cells c. memory B-cells d. B and C BACK TO GAME ANSWER

25. Topic 3: $200 Answer Which of the following cells become activated only if the same antigen appears in the body at a later date? a. cytotoxic T-cells b. memory T-cells c. memory B-cells d. B and C BACK TO GAME

26. Topic 3: $300 Question Which type of lymphocyte is responsible for “cell-mediated immunity?” a. activated T-cells b. B-cells c. natural killer cells d. suppressor T-cells BACK TO GAME ANSWER

27. Topic 3: $300 Answer Which type of lymphocyte is responsible for “cell-mediated immunity?” a. activated T-cells b. B-cells c. natural killer cells d. suppressor T-cells BACK TO GAME

28. Topic 3: $400 Question Which of the following types of lymphocytes are also known as “large granular lymphocytes?” a. memory T-cells b. helper T-cells c. natural killer cells d. suppressor T-cells BACK TO GAME ANSWER

29. Topic 3: $400 Answer Which of the following types of lymphocytes are also known as “large granular lymphocytes?” a. memory T-cells b. helper T-cells c. natural killer cells d. suppressor T-cells BACK TO GAME

30. Topic 3: $500 Question Which type of lymphocyte is seldom found in the thymus? a. natural killer cells b. suppressor T-cells c. B-cells d. helper T-cells BACK TO GAME ANSWER

31. Topic 3: $500 Answer Which type of lymphocyte is seldom found in the thymus? a. natural killer cells b. suppressor T-cells c. B-cells d. helper T-cells BACK TO GAME

32. Topic 4: $100 Question Typical lymphoid nodules often have a pale central zone, called a ____, which contains activated, dividing ____. a. germinal center, dendritic cells b. germinal center, lymphocytes c. deep cortex, dendritic cells d. medulla, lymphocytes BACK TO GAME ANSWER

33. Topic 4: $100 Answer Typical lymphoid nodules often have a pale central zone, called a ____, which contains activated, dividing ____. a. germinal center, dendritic cells b. germinal center, lymphocytes c. deep cortex, dendritic cells d. medulla, lymphocytes BACK TO GAME

34. Topic 4: $200 Question Where is mucosa-associated lymphoid tissue (MALT) found? a. in the adenoids b. in the digestive tract c. in the respiratory tract d. in the splenic red pulp BACK TO GAME ANSWER

35. Topic 4: $200 Answer Where is mucosa-associated lymphoid tissue (MALT) found? a. in the adenoids b. in the digestive tract c. in the respiratory tract d. in the splenic red pulp BACK TO GAME

36. Topic 4: $300 Question Lymphoid nodules are typically ____ in shape, and average around ____ in diameter. a. round, 1 cm b. round, 5 mm c. oval, 1 mm d. oval, 2 cm BACK TO GAME ANSWER

37. Topic 4: $300 Answer Lymphoid nodules are typically ____ in shape, and average around ____ in diameter. a. round, 1 cm b. round, 5 mm c. oval, 1 mm d. oval, 2 cm BACK TO GAME

38. Topic 4: $400 Question Where are aggregated lymphoid nodules, known as Peyer’s patches, found? a. in the urinary bladder b. in the small intestine c. in the lungs d. in the adenoids BACK TO GAME ANSWER

39. Topic 4: $400 Answer Where are aggregated lymphoid nodules, known as Peyer’s patches, found? a. in the urinary bladder b. in the small intestine c. in the lungs d. in the adenoids BACK TO GAME

40. Topic 4: $500 Question How many tonsils are normally found in the human body? a. two b. four c. five d. six BACK TO GAME ANSWER

41. Topic 4: $500 Answer How many tonsils are normally found in the human body? a. two b. four c. five d. six BACK TO GAME

42. Topic 5: $100 Question Which region of the lymph node contains a meshwork of branching reticular fibers, macrophages and dendritic cells? a. medulla b. outer cortex c. paracortical area d. subcapsular space BACK TO GAME ANSWER

43. Topic 5: $100 Answer Which region of the lymph node contains a meshwork of branching reticular fibers, macrophages and dendritic cells? a. medulla b. outer cortex c. paracortical area d. subcapsular space BACK TO GAME

44. Topic 5: $200 Question Which of the following areas of a typical lymph node is dominated by T-cells? a. the outer cortex b. the medulla c. the deep cortical area d. the medullary cords BACK TO GAME ANSWER

45. Topic 5: $200 Answer Which of the following areas of a typical lymph node is dominated by T-cells? a. the outer cortex b. the medulla c. the deep cortical area d. the medullary cords BACK TO GAME

46. Topic 5: $300 Question Which of the following statements regarding the thymus is/are false? a. The thymic medulla contains lymphoid stem cells that divide rapidly, producing daughter cells that mature into T-cells. b.The capsule that covers the thymus divides it into two thymic lobes. c. The thymus reaches its greatest size, relative to body size, in the first year or two after birth. d. None of the statements is false. BACK TO GAME ANSWER

47. Topic 5: $300 Answer Which of the following statements regarding the thymus is/are false? a. The thymic medulla contains lymphoid stem cells that divide rapidly, producing daughter cells that mature into T-cells. b.The capsule that covers the thymus divides it into two thymic lobes. c. The thymus reaches its greatest size, relative to body size, in the first year or two after birth. d. None of the statements is false. BACK TO GAME

48. Topic 5: $400 Question The increased incidence of ____ in the elderly reflects the fact that lymphoid surveillance declines, and ____ cells are not eliminated as effectively. a. cancer, natural killer b. allergies, T-cells c. cancer, tumor d. allergies, antigens BACK TO GAME ANSWER

49. Topic 5: $400 Answer The increased incidence of ____ in the elderly reflects the fact that lymphoid surveillance declines, and ____ cells are not eliminated as effectively. a. cancer, natural killer b. allergies, T-cells c. cancer, tumor d. allergies, antigens BACK TO GAME

50. Topic 5: $500 Question Which splenic surface/area contains indentations known as the gastric area and renal area? a. diaphragmatic surface b. hilus c. gastrosplenic area d. visceral surface BACK TO GAME ANSWER

51. Topic 5: $500 Answer Which splenic surface/area contains indentations known as the gastric area and renal area? a. diaphragmatic surface b. hilus c. gastrosplenic area d. visceral surface BACK TO GAME

52. FINAL ROUND Question What is the correct order of events which occur when defenses against bacterial pathogens are initiated? 1 - Antibody production by plasmocytes 2 - Activation of B-cells 3 - Macrophage activation 4 - Activation of helper T-cells 5 - Antigen presentation a. 5-3-2-4-1 b. 3-5-4-2-1 c. 5-3-4-2-1 d. 3-5-2-4-1 BACK TO GAME ANSWER

53. FINAL ROUND Answer What is the correct order of events which occur when defenses against bacterial pathogens are initiated? 1 - Antibody production by plasmocytes 2 - Activation of B-cells 3 - Macrophage activation 4 - Activation of helper T-cells 5 - Antigen presentation a. 5-3-2-4-1 b. 3-5-4-2-1 c. 5-3-4-2-1 d. 3-5-2-4-1 BACK TO GAME