1. FASCIOLA HEPATICA

2. FASCIOLA hepatica
Disease: Fascioliasis & liver rot in animals. Distribution: - Common in cattle & sheep raising countries.

3. FASCIOLA hepatica Definitive host : man
Reservoir host: Cattle, sheep ,goats, buffaloes
Habitat: Bile ducts.
Intermediate host: Lymnaea snails.
Infective stage : Encysted metacercaria.

4. Mode of infection
Ingestion of raw vegitation or water containing encysted metacercaria.

5. Life cycle:

6. Adult FASCIOLA Hepatica

7. Egg: Size : 140 X 70 µm. Shape: Oval, Thin walled with operculum.
Color : Yellowish brown (bile stained).
Contents : Ovum & yolk cells (immature).

8. Miracidium
Pyriform.
Ciliated.

9. Lymnaea snails

10. Cercaria (Leptocercus)
Last larval stage inside the snail.
No sexual organs.
Cystogenous glands (help in passing out of snail & in encysting on vegetations or water).
Tail: simple & helps in leaving the snail.

11. Encysted Metacercaria
Without tail.
Surrounded by a cyst
wall.

12. Clinical Picture : Fever. Pain & tenderness in right hypochondrium.
Biliary colics.
Hepatomegaly,
Jaundice.
Vomiting & diarrhoea.
Toxaemia.
Anaemia & eosinophilia.

13. Diagnosis Clinically : A highly suggestive tetrad of: Fever.
Hepatomegaly.
Pain & tenderness in the right hypochondrium.
Eosinophilia.

14. Diagnosis II- Laboratory : a. Direct methods
Stool examination by direct smear & concentration methods to find the characteristic eggs.
Bile aspiration from the duodenum & examine for eggs.
US.
Computerized tomography (C.T).

15. Diagnosis

16. Diagnosis
b. Indirect Methods
ELISA, IHA ,CIEP
Eosinophilia.

17. Thank You